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| 25.03.2023 | 16:00 | Atlas Guadalajara | - | Atlético San Luis | 0:3 (0:2) | |
| 16:00 | Cruz Azul | - | Gallos Blancos | 1:1 (0:0) | ||
| 16:00 | Club León | - | Deportivo Guadalajara | 0:1 (0:1) | ||
| 16:00 | UANL Tigres | - | Club Tijuana | 2:1 (2:0) | ||
| 16:00 | Pumas UNAM | - | FC Juárez | 1:0 (1:0) | ||
| 18:30 | Club Necaxa | - | Puebla FC | 1:1 (1:0) | ||
| 23:00 | CF América | - | CF Pachuca | 1:2 (0:2) | ||
| 23:00 | CF Monterrey | - | Santos Laguna | 1:2 (1:1) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| 1 | |||||||||
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
CF Pachuca | 11 | 8 | 1 | 2 | 21:12 | 9 | 25 |
| 2 |
|
Pumas UNAM | 11 | 7 | 3 | 1 | 20:8 | 12 | 24 |
| 3 |
|
CF América | 11 | 5 | 2 | 4 | 26:20 | 6 | 17 |
| 4 |
|
FC Juárez | 11 | 4 | 4 | 3 | 15:13 | 2 | 16 |
| 5 |
|
Club Necaxa | 10 | 3 | 5 | 2 | 23:22 | 1 | 14 |
| 6 |
|
Puebla FC | 11 | 2 | 4 | 5 | 17:23 | -6 | 10 |
| 7 |
|
Deportivo Toluca | 10 | 3 | 1 | 6 | 10:19 | -9 | 10 |
| 8 |
|
Cruz Azul | 10 | 2 | 3 | 5 | 11:16 | -5 | 9 |
| 9 |
|
Gallos Blancos | 11 | 1 | 3 | 7 | 11:21 | -10 | 6 |
| 2 | |||||||||
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Santos Laguna | 10 | 8 | 1 | 1 | 18:7 | 11 | 25 |
| 2 |
|
Deportivo Guadalajara | 11 | 5 | 3 | 3 | 17:15 | 2 | 18 |
| 3 |
|
UANL Tigres | 11 | 5 | 3 | 3 | 19:20 | -1 | 18 |
| 4 |
|
CF Monterrey | 11 | 5 | 2 | 4 | 26:17 | 9 | 17 |
| 5 |
|
Club León | 11 | 5 | 2 | 4 | 17:16 | 1 | 17 |
| 6 |
|
Mazatlán FC | 10 | 3 | 4 | 3 | 12:14 | -2 | 13 |
| 7 |
|
Atlas Guadalajara | 11 | 3 | 2 | 6 | 17:22 | -5 | 11 |
| 8 |
|
Atlético San Luis | 10 | 2 | 2 | 6 | 13:20 | -7 | 8 |
| 9 |
|
Club Tijuana | 11 | 1 | 3 | 7 | 11:19 | -8 | 6 |
| Play-offs | |
| Play-offs |
