 |
 |
|
|
| 18.03.2021 | 16:30 | CF Pachuca | - | UANL Tigres | 2:2 (1:1) | |
| 19.03.2021 | 18:15 | Club Necaxa | - | FC Juárez | 1:0 (1:0) | |
| 19:30 | Mazatlán FC | - | CF América | 1:2 (0:2) | ||
| 20.03.2021 | 18:30 | CF Monterrey | - | Deportivo Guadalajara | 0:1 (0:0) | |
| 18:30 | Cruz Azul | - | Atlas Guadalajara | 0:2 (0:0) | ||
| 19:00 | Atlético San Luis | - | Pumas UNAM | 0:3 (0:2) | ||
| 20:45 | Club Tijuana | - | Gallos Blancos | 3:2 (3:1) | ||
| 21.03.2021 | 16:00 | Santos Laguna | - | Club León | 1:1 (0:1) | |
| 18:30 | Deportivo Toluca | - | Puebla FC | 1:1 (1:0) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
CF Pachuca | 12 | 8 | 3 | 1 | 32:14 | 18 | 40 |
| 2 |
|
Atlas Guadalajara | 12 | 7 | 1 | 4 | 22:17 | 5 | 34 |
| 3 |
|
Santos Laguna | 12 | 7 | 2 | 3 | 26:19 | 7 | 32 |
| 4 |
|
UANL Tigres | 12 | 7 | 3 | 2 | 21:12 | 9 | 31 |
| 5 |
|
Club León | 12 | 7 | 3 | 2 | 23:16 | 7 | 31 |
| 6 |
|
Deportivo Guadalajara | 12 | 6 | 4 | 2 | 22:13 | 9 | 29 |
| 7 |
|
Club Tijuana | 12 | 6 | 1 | 5 | 21:19 | 2 | 28 |
| 8 |
|
Mazatlán FC | 12 | 4 | 4 | 4 | 16:21 | -5 | 26 |
| 9 |
|
Deportivo Toluca | 12 | 4 | 5 | 3 | 20:17 | 3 | 25 |
| 10 |
|
Pumas UNAM | 12 | 5 | 2 | 5 | 15:12 | 3 | 25 |
| 11 |
|
CF Monterrey | 12 | 5 | 2 | 5 | 17:17 | 0 | 24 |
| 12 |
|
Cruz Azul | 12 | 5 | 1 | 6 | 19:20 | -1 | 24 |
| 13 |
|
Puebla FC | 12 | 4 | 3 | 5 | 18:19 | -1 | 22 |
| 14 |
|
Club Necaxa | 12 | 3 | 2 | 7 | 16:20 | -4 | 21 |
| 15 |
|
FC Juárez | 12 | 4 | 1 | 7 | 15:17 | -2 | 20 |
| 16 |
|
Atlético San Luis | 12 | 1 | 2 | 9 | 10:33 | -23 | 17 |
| 17 |
|
CF América | 12 | 3 | 0 | 9 | 14:29 | -15 | 15 |
| 18 |
|
Gallos Blancos | 12 | 2 | 1 | 9 | 16:28 | -12 | 13 |
| Play-offs |
