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| 27.11.2010 | 13:00 | FK Pelister | - | Vardar Skopje | 1:2 (0:2) | |
| 13:00 | FK Turnovo | - | FK Skopje | 1:0 (0:0) | ||
| 13:00 | FK Renova | - | Napredok Kičevo | 5:0 (1:0) | ||
| 13:00 | Sileks Kratovo | - | KF Shkëndija 79 | 1:1 (1:1) | ||
| 13:00 | Metalurg Skopje | - | FK Teteks | 1:0 (1:0) | ||
| 13:00 | FK Rabotnički | - | FK Bregalnica Štip | 3:1 (2:0) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FK Renova | 16 | 9 | 4 | 3 | 22:8 | 14 | 31 |
| 2 |
|
KF Shkëndija 79 | 16 | 8 | 5 | 3 | 26:9 | 17 | 29 |
| 3 |
|
FK Rabotnički | 16 | 7 | 5 | 4 | 20:15 | 5 | 26 |
| 4 |
|
Metalurg Skopje | 16 | 7 | 5 | 4 | 17:12 | 5 | 26 |
| 5 |
|
FK Turnovo | 16 | 8 | 2 | 6 | 18:15 | 3 | 26 |
| 6 |
|
Napredok Kičevo | 16 | 7 | 3 | 6 | 17:19 | -2 | 24 |
| 7 |
|
FK Teteks | 16 | 6 | 5 | 5 | 15:11 | 4 | 23 |
| 8 |
|
FK Bregalnica Štip | 16 | 7 | 1 | 8 | 16:21 | -5 | 22 |
| 9 |
|
Sileks Kratovo | 16 | 5 | 5 | 6 | 16:20 | -4 | 20 |
| 10 |
|
FK Skopje | 16 | 5 | 4 | 7 | 11:12 | -1 | 19 |
| 11 |
|
Vardar Skopje | 16 | 4 | 1 | 11 | 12:27 | -15 | 10 |
| 12 |
|
FK Pelister | 16 | 2 | 2 | 12 | 9:30 | -21 | 8 |
| Champions League Kwali. | |
| Europa League | |
| Promotie en degradatie | |
| Degradatie |
