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| 07.05.2022 | 17:00 | FC Echallens | - | FC Bulle | 1:0 (0:0) | |
| 17:00 | FC Monthey | - | FC Thun Berner Oberland II | 2:1 (1:0) | ||
| 17:00 | US Terre Sainte | - | CS Chênois | 2:3 (1:1) | ||
| 17:00 | FC Lancy | - | Martigny Sports | 1:2 (0:1) | ||
| 17:00 | FC Naters | - | FC La Chaux-de-Fonds | 0:3 (0:2) | ||
| 17:30 | Vevey-Sports | - | FC La Sarraz-Eclépens | 2:0 (1:0) | ||
| 08.05.2022 | 14:00 | Team Vaud Lausanne [U21] | - | FC Meyrin | 1:1 (0:0) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FC Echallens | 23 | 16 | 3 | 4 | 51:29 | 22 | 51 |
| 2 |
|
Vevey-Sports | 23 | 15 | 3 | 5 | 39:24 | 15 | 48 |
| 3 |
|
FC Bulle | 23 | 13 | 6 | 4 | 59:18 | 41 | 45 |
| 4 |
|
FC Thun Berner Oberland II | 23 | 14 | 2 | 7 | 51:32 | 19 | 44 |
| 5 |
|
FC Meyrin | 23 | 10 | 6 | 7 | 41:28 | 13 | 36 |
| 6 |
|
FC Monthey | 23 | 8 | 7 | 8 | 34:39 | -5 | 31 |
| 7 |
|
CS Chênois | 23 | 9 | 3 | 11 | 34:41 | -7 | 30 |
| 8 |
|
FC Naters | 23 | 8 | 5 | 10 | 32:34 | -2 | 29 |
| 9 |
|
FC La Chaux-de-Fonds | 23 | 8 | 3 | 12 | 34:50 | -16 | 27 |
| 10 |
![Team Vaud Lausanne [U21], Zwitserland](https://s.hs-data.com/bilder/wappen/mini/25867.gif?fallback=png "Team Vaud Lausanne [U21], Zwitserland"){kind=small}
|
Team Vaud Lausanne [U21] | 23 | 7 | 5 | 11 | 41:45 | -4 | 26 |
| 11 |
|
FC Lancy | 23 | 6 | 6 | 11 | 34:42 | -8 | 24 |
| 12 |
|
US Terre Sainte | 23 | 7 | 1 | 15 | 31:49 | -18 | 22 |
| 13 |
|
Martigny Sports | 23 | 7 | 1 | 15 | 27:60 | -33 | 22 |
| 14 |
|
FC La Sarraz-Eclépens | 23 | 6 | 3 | 14 | 39:56 | -17 | 21 |
| Play-offs | |
| Degradatie |
