| 22. Ronde | 04.02.2022 | Extremadura UD | - | UD SS Reyes | 0:6 | ||||
| 26. Ronde | 05.03.2022 | SD Logroñés | - | UD SS Reyes | 1:0 | ||||
| 27. Ronde | 12.03.2022 | UD SS Reyes | - | CD Calahorra | 0:3 |  |
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| 29. Ronde | 27.03.2022 | Racing Ferrol | - | UD SS Reyes | 1:0 | ||||
| 31. Ronde | 09.04.2022 | Celta de Vigo B | - | UD SS Reyes | 1:2 | ||||
| 32. Ronde | 17.04.2022 | UD SS Reyes | - | Cultural Leonesa | 0:3 | ||||
| 34. Ronde | 01.05.2022 | UD SS Reyes | - | Real Valladolid B | 1:1 | ||||
| 35. Ronde | 08.05.2022 | Rayo Majadahonda | - | UD SS Reyes | 1:0 | ||||
| 36. Ronde | 13.05.2022 | UD SS Reyes | - | Unionistas CF | 1:2 | |
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| 37. Ronde | 21.05.2022 | CD Tudelano | - | UD SS Reyes | 0:2 | ||||
| 38. Ronde | 27.05.2022 | UD SS Reyes | - | Athletic Club B | 2:0 |
Spanje