| 1. Ronde | 08.01.2022 | Mazatlán FC [] | - | Atlas Guadalajara [] | 0:4 | ||||
| 2. Ronde | 16.01.2022 | Atlético San Luis [] | - | Mazatlán FC [] | 2:1 | ||||
| 7. Ronde | 19.02.2022 | Deportivo Guadalajara [] | - | Mazatlán FC [] | 2:0 | ||||
| 8. Ronde | 26.02.2022 | Mazatlán FC [] | - | Santos Laguna [] | 0:3 | ||||
| 10. Ronde | 12.03.2022 | Mazatlán FC [] | - | CF Monterrey [] | 1:3 | ||||
| 11. Ronde | 19.03.2022 | UANL Tigres [] | - | Mazatlán FC [] | 5:0 |
Mexico