| 1. Ronde | 25.06.2022 | Atlético San Luis [] | - | CF Monterrey [] | 0:5 | ||||
| 3. Ronde | 09.07.2022 | Mazatlán FC [] | - | Atlético San Luis [] | 1:2 | ||||
| 4. Ronde | 16.07.2022 | Atlético San Luis [] | - | Santos Laguna [] | 2:7 | ||||
| 5. Ronde | 23.07.2022 | Atlas Guadalajara [] | - | Atlético San Luis [] | 8:1 | ||||
| 6. Ronde | 30.07.2022 | Atlético San Luis [] | - | UANL Tigres [] | 1:4 |  |
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| 7. Ronde | 05.08.2022 | Club León [] | - | Atlético San Luis [] | 2:0 | |
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| 8. Ronde | 13.08.2022 | Atlético San Luis [] | - | Deportivo Guadalajara [] | 2:1 | ||||
| 9. Ronde | 20.08.2022 | Club Tijuana [] | - | Atlético San Luis [] | 6:3 | ||||
| 10. Ronde | 27.08.2022 | CF Monterrey [] | - | Atlético San Luis [] | 5:1 | ||||
| 11. Ronde | 03.09.2022 | Atlético San Luis [] | - | Club Tijuana [] | 0:2 | |
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| 12. Ronde | 11.09.2022 | Deportivo Guadalajara [] | - | Atlético San Luis [] | 3:1 | ||||
| 13. Ronde | 18.09.2022 | Atlético San Luis [] | - | Club León [] | 0:4 | ||||
| 16. Ronde | 08.10.2022 | Santos Laguna [] | - | Atlético San Luis [] | 4:0 |
Mexico