| 1. Ronde | 25.06.2022 | Mazatlán FC [] | - | Club Tijuana [] | 0:3 |  |
|||
| 2. Ronde | 02.07.2022 | Club Tijuana [] | - | Santos Laguna [] | 2:0 | ||||
| 3. Ronde | 09.07.2022 | Atlas Guadalajara [] | - | Club Tijuana [] | 0:0 | ||||
| 4. Ronde | 16.07.2022 | Club Tijuana [] | - | UANL Tigres [] | 8:2 | ||||
| 5. Ronde | 23.07.2022 | Club León [] | - | Club Tijuana [] | 0:1 | ||||
| 6. Ronde | 31.07.2022 | Club Tijuana [] | - | Deportivo Guadalajara [] | 3:1 | ||||
| 8. Ronde | 13.08.2022 | CF Monterrey [] | - | Club Tijuana [] | 3:2 | ||||
| 10. Ronde | 27.08.2022 | Club Tijuana [] | - | Mazatlán FC [] | 4:0 | ||||
| 11. Ronde | 03.09.2022 | Atlético San Luis [] | - | Club Tijuana [] | 0:2 |  |
|||
| 12. Ronde | 10.09.2022 | Club Tijuana [] | - | CF Monterrey [] | 2:2 | ||||
| 14. Ronde | 25.09.2022 | Deportivo Guadalajara [] | - | Club Tijuana [] | 2:1 | ||||
| 16. Ronde | 08.10.2022 | UANL Tigres [] | - | Club Tijuana [] | 1:0 | ||||
| 15. Ronde | 12.10.2022 | Club Tijuana [] | - | Club León [] | 5:1 | ||||
| 18. Ronde | 22.10.2022 | Santos Laguna [] | - | Club Tijuana [] | 1:0 |
Mexico