| 2. Ronde | 15.01.2022 | CF Monterrey [] | - | Deportivo Guadalajara [] | 1:1 | ||||
| 7. Ronde | 19.02.2022 | Club Tijuana [] | - | CF Monterrey [] | 1:1 | ||||
| 8. Ronde | 26.02.2022 | CF Monterrey [] | - | Atlético San Luis [] | 7:0 | ||||
| 10. Ronde | 12.03.2022 | Mazatlán FC [] | - | CF Monterrey [] | 1:3 | ||||
| 17. Ronde | 30.04.2022 | Club León [] | - | CF Monterrey [] | 1:1 |
Mexico