| 1. Ronde | 28.07.2020 | CF Pachuca | - | CF América | 1:2 | ||||
| 6. Ronde | 23.08.2020 | CF América | - | CF Monterrey | 1:3 |  |
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| 7. Ronde | 30.08.2020 | Atlético San Luis | - | CF América | 1:2 | |
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| 8. Ronde | 03.09.2020 | CF América | - | Mazatlán FC | 3:1 | ||||
| 9. Ronde | 09.09.2020 | Puebla FC | - | CF América | 2:3 | |
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| 10. Ronde | 13.09.2020 | CF América | - | Deportivo Toluca | 1:1 | ||||
| 11. Ronde | 20.09.2020 | CF América | - | Deportivo Guadalajara | 1:0 | ||||
| 12. Ronde | 28.09.2020 | Cruz Azul | - | CF América | 0:0 |  |
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| 15. Ronde | 25.10.2020 | CF América | - | Atlas Guadalajara | 1:0 | ||||
| 16. Ronde | 02.11.2020 | CF América | - | UANL Tigres | 3:1 | |
Argentinië