| 2. Ronde | 25.09.2021 | CF Monterrey [] | - | Mazatlán FC [] | 4:1 | ||||
| 3. Ronde | 02.10.2021 | Atlas Guadalajara [] | - | CF Monterrey [] | 2:1 | ||||
| 5. Ronde | 16.10.2021 | Santos Laguna [] | - | CF Monterrey [] | 4:1 | ||||
| 6. Ronde | 23.10.2021 | UANL Tigres [] | - | CF Monterrey [] | 2:1 | ||||
| 7. Ronde | 30.10.2021 | CF Monterrey [] | - | Deportivo Guadalajara [] | 1:3 |  |
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| 10. Ronde | 20.11.2021 | Club Necaxa [] | - | CF Monterrey [] | 1:1 |  |
Mexico