| 3. Ronde | 26.09.2020 | Valencia CF | - | SD Huesca | 1:1 | ||||
| 4. Ronde | 30.09.2020 | SD Huesca | - | Atlético Madrid | 0:0 | ||||
| 5. Ronde | 03.10.2020 | Elche CF | - | SD Huesca | 0:0 | ||||
| 6. Ronde | 18.10.2020 | SD Huesca | - | Real Valladolid | 2:2 | ||||
| 7. Ronde | 25.10.2020 | Real Sociedad | - | SD Huesca | 4:1 | ||||
| 8. Ronde | 31.10.2020 | Real Madrid | - | SD Huesca | 4:1 | ||||
| 9. Ronde | 07.11.2020 | SD Huesca | - | SD Eibar | 1:1 | ||||
| 11. Ronde | 28.11.2020 | SD Huesca | - | Sevilla FC | 0:1 | ||||
| 12. Ronde | 06.12.2020 | Granada CF | - | SD Huesca | 3:3 | ||||
| 13. Ronde | 12.12.2020 | SD Huesca | - | Deportivo Alavés | 1:0 |  |
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| 14. Ronde | 18.12.2020 | Athletic Club | - | SD Huesca | 2:0 | ||||
| 15. Ronde | 22.12.2020 | SD Huesca | - | Levante UD | 1:1 | |
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| 16. Ronde | 30.12.2020 | Celta de Vigo | - | SD Huesca | 2:1 | ||||
| 17. Ronde | 03.01.2021 | SD Huesca | - | FC Barcelona | 0:1 | |
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| 18. Ronde | 11.01.2021 | SD Huesca | - | Real Betis | 0:2 | |
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| 19. Ronde | 20.01.2021 | Getafe CF | - | SD Huesca | 1:0 | |
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| 20. Ronde | 23.01.2021 | SD Huesca | - | Villarreal CF | 0:0 | |
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| 22. Ronde | 06.02.2021 | SD Huesca | - | Real Madrid | 1:2 | ||||
| 26. Ronde | 07.03.2021 | SD Huesca | - | Celta de Vigo | 3:4 | ||||
| 27. Ronde | 15.03.2021 | FC Barcelona | - | SD Huesca | 4:1 |
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