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| 15.12.2020 | 22:00 | Real Madrid | - | Athletic Bilbao | 3:1 (1:0) | |
| 16.12.2020 | 21:00 | FC Barcelona | - | Real Sociedad | 2:1 (2:1) | |
| 19.01.2021 | 19:00 | Cádiz CF | - | Levante UD | 2:2 (2:2) | |
| 19:00 | Real Valladolid | - | Elche CF | 2:2 (0:2) | ||
| 21:30 | Deportivo Alavés | - | Sevilla FC | 1:2 (1:2) | ||
| 20.01.2021 | 19:00 | Getafe CF | - | SD Huesca | 1:0 (0:0) | |
| 21:00 | Real Betis | - | Celta de Vigo | 2:1 (2:1) | ||
| 21:30 | Villarreal CF | - | Granada CF | 2:2 (1:1) | ||
| 21.01.2021 | 19:00 | Valencia CF | - | CA Osasuna | 1:1 (0:1) | |
| 21:30 | SD Eibar | - | Atlético Madrid | 1:2 (1:1) |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Atlético Madrid | 19 | 15 | 3 | 1 | 36:9 | 27 | 48 |
| 2 |
|
Real Madrid | 19 | 12 | 4 | 3 | 32:15 | 17 | 40 |
| 3 |
|
FC Barcelona | 19 | 11 | 4 | 4 | 40:17 | 23 | 37 |
| 4 |
|
Sevilla FC | 19 | 11 | 3 | 5 | 25:16 | 9 | 36 |
| 5 |
|
Villarreal CF | 19 | 8 | 9 | 2 | 28:19 | 9 | 33 |
| 6 |
|
Real Sociedad | 19 | 8 | 6 | 5 | 29:16 | 13 | 30 |
| 7 |
|
Granada CF | 19 | 8 | 4 | 7 | 23:31 | -8 | 28 |
| 8 |
|
Real Betis | 19 | 8 | 2 | 9 | 24:32 | -8 | 26 |
| 9 |
|
Cádiz CF | 19 | 6 | 6 | 7 | 17:24 | -7 | 24 |
| 10 |
|
Levante UD | 19 | 5 | 8 | 6 | 26:27 | -1 | 23 |
| 11 |
|
Getafe CF | 19 | 6 | 5 | 8 | 16:20 | -4 | 23 |
| 12 |
|
Celta de Vigo | 19 | 6 | 5 | 8 | 23:30 | -7 | 23 |
| 13 |
|
Athletic Bilbao | 19 | 6 | 3 | 10 | 22:24 | -2 | 21 |
| 14 |
|
Valencia CF | 19 | 4 | 8 | 7 | 25:26 | -1 | 20 |
| 15 |
|
SD Eibar | 19 | 4 | 7 | 8 | 16:20 | -4 | 19 |
| 16 |
|
Real Valladolid | 19 | 4 | 7 | 8 | 18:27 | -9 | 19 |
| 17 |
|
Deportivo Alavés | 19 | 4 | 6 | 9 | 17:25 | -8 | 18 |
| 18 |
|
Elche CF | 19 | 3 | 8 | 8 | 16:28 | -12 | 17 |
| 19 |
|
CA Osasuna | 19 | 3 | 7 | 9 | 16:28 | -12 | 16 |
| 20 |
|
SD Huesca | 19 | 1 | 9 | 9 | 14:29 | -15 | 12 |
| Champions League | |
| Europa League | |
| Europa League Kwali. | |
| Degradatie |
