| 2. Ronde | 20.09.2020 | Real Betis | - | Real Valladolid | 2:0 | ||||
| 3. Ronde | 27.09.2020 | Real Valladolid | - | Celta de Vigo | 1:1 |  |
|||
| 4. Ronde | 30.09.2020 | Real Madrid | - | Real Valladolid | 1:0 | ||||
| 5. Ronde | 03.10.2020 | Real Valladolid | - | SD Eibar | 1:2 | ||||
| 10. Ronde | 22.11.2020 | Granada CF | - | Real Valladolid | 1:3 | ||||
| 11. Ronde | 27.11.2020 | Real Valladolid | - | Levante UD | 1:1 | ||||
| 12. Ronde | 05.12.2020 | Atlético Madrid | - | Real Valladolid | 2:0 | |
|||
| 13. Ronde | 11.12.2020 | Real Valladolid | - | CA Osasuna | 3:2 | ||||
| 15. Ronde | 22.12.2020 | Real Valladolid | - | FC Barcelona | 0:3 | ||||
| 17. Ronde | 02.01.2021 | Getafe CF | - | Real Valladolid | 0:1 | ||||
| 18. Ronde | 10.01.2021 | Real Valladolid | - | Valencia CF | 0:1 | ||||
| 29. Ronde | 05.04.2021 | FC Barcelona | - | Real Valladolid | 1:0 | ||||
| 30. Ronde | 11.04.2021 | Real Valladolid | - | Granada CF | 1:2 | ||||
| 34. Ronde | 02.05.2021 | Real Valladolid | - | Real Betis | 1:1 | |
|||
| 35. Ronde | 09.05.2021 | Valencia CF | - | Real Valladolid | 3:0 | ||||
| 37. Ronde | 16.05.2021 | Real Sociedad | - | Real Valladolid | 4:1 |
Spanje