| 6. Ronde | 12.09.2021 | FC Lugano | - | FC Basel 1893 | 1:1 | ||||
| 8. Ronde | 26.09.2021 | FC Basel 1893 | - | FC Zürich | 3:1 | ||||
| 9. Ronde | 03.10.2021 | FC Basel 1893 | - | FC Luzern | 1:1 | ||||
| 13. Ronde | 07.11.2021 | FC Basel 1893 | - | FC St. Gallen | 0:1 | ||||
| 15. Ronde | 28.11.2021 | FC Luzern | - | FC Basel 1893 | 1:3 | ||||
| 16. Ronde | 05.12.2021 | FC Basel 1893 | - | FC Lausanne-Sport | 1:1 |  |
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| 18. Ronde | 19.12.2021 | FC Basel 1893 | - | Grasshopper Club Zürich | 2:2 | ||||
| 21. Ronde | 13.02.2022 | BSC Young Boys | - | FC Basel 1893 | 3:1 | ||||
| 22. Ronde | 19.02.2022 | FC Basel 1893 | - | FC Lausanne-Sport | 3:0 | ||||
| 24. Ronde | 03.03.2022 | FC Basel 1893 | - | FC St. Gallen | 2:2 | ||||
| 26. Ronde | 13.03.2022 | FC Basel 1893 | - | Servette FC | 2:0 | ||||
| 27. Ronde | 20.03.2022 | Grasshopper Club Zürich | - | FC Basel 1893 | 2:4 | ||||
| 30. Ronde | 18.04.2022 | FC Sion | - | FC Basel 1893 | 0:0 | ||||
| 31. Ronde | 24.04.2022 | FC Basel 1893 | - | FC Luzern | 3:0 | ||||
| 32. Ronde | 01.05.2022 | FC Basel 1893 | - | FC Zürich | 0:2 | ||||
| 33. Ronde | 08.05.2022 | FC Lausanne-Sport | - | FC Basel 1893 | 0:0 | ||||
| 34. Ronde | 12.05.2022 | FC Basel 1893 | - | Grasshopper Club Zürich | 1:1 | ||||
| 35. Ronde | 19.05.2022 | Servette FC | - | FC Basel 1893 | 0:0 |
Guinea-Bissau