| 1. Ronde | 13.03.2021 | San Telmo | - | Barracas Central | 1:1 | ||||
| 2. Ronde | 22.03.2021 | Independiente Rivadavia | - | San Telmo | 4:3 | ||||
| 3. Ronde | 28.03.2021 | San Telmo | - | Atlético Rafaela | 0:0 | ||||
| 4. Ronde | 04.04.2021 | Guillermo Brown | - | San Telmo | 1:2 |  |
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| 5. Ronde | 11.04.2021 | San Telmo | - | Brown de Adrogué | 2:1 | |
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| 6. Ronde | 18.04.2021 | San Martín de San Juan | - | San Telmo | 5:0 | ||||
| 9. Ronde | 10.05.2021 | Defensores de Belgrano | - | San Telmo | 0:0 | ||||
| 10. Ronde | 16.05.2021 | San Telmo | - | Ramón Santamarina | 2:2 | ||||
| 11. Ronde | 11.06.2021 | Almagro | - | San Telmo | 1:0 | ||||
| 12. Ronde | 17.06.2021 | San Telmo | - | Güemes de SdE | 1:1 | |
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| 13. Ronde | 23.06.2021 | Deportivo Morón | - | San Telmo | 2:0 | ||||
| 14. Ronde | 27.06.2021 | San Telmo | - | Ferro Carril Oeste | 1:0 | ||||
| 15. Ronde | 03.07.2021 | Tristan Suárez | - | San Telmo | 1:1 | ||||
| 16. Ronde | 10.07.2021 | San Telmo | - | Gimnasia de Jujuy | 0:0 | ||||
| 17. Ronde | 19.07.2021 | Instituto de Córdoba | - | San Telmo | 1:0 |
Argentinië