| 1. Ronde | 12.09.2020 | Granada CF | - | Athletic Club | 2:0 |  |
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| 2. Ronde | 20.09.2020 | Granada CF | - | Deportivo Alavés | 2:1 | ||||
| 3. Ronde | 27.09.2020 | Atlético Madrid | - | Granada CF | 6:1 | ||||
| 5. Ronde | 04.10.2020 | Cádiz CF | - | Granada CF | 1:1 | ||||
| 6. Ronde | 17.10.2020 | Granada CF | - | Sevilla FC | 1:0 | ||||
| 8. Ronde | 01.11.2020 | Granada CF | - | Levante UD | 1:1 | ||||
| 10. Ronde | 22.11.2020 | Granada CF | - | Real Valladolid | 1:3 | ||||
| 11. Ronde | 29.11.2020 | Celta de Vigo | - | Granada CF | 3:1 | ||||
| 12. Ronde | 06.12.2020 | Granada CF | - | SD Huesca | 3:3 | ||||
| 13. Ronde | 13.12.2020 | Elche CF | - | Granada CF | 0:1 | ||||
| 14. Ronde | 20.12.2020 | Granada CF | - | Real Betis | 2:0 | ||||
| 15. Ronde | 23.12.2020 | Real Madrid | - | Granada CF | 2:0 | ||||
| 18. Ronde | 09.01.2021 | Granada CF | - | FC Barcelona | 0:4 | ||||
| 4. Ronde | 12.01.2021 | Granada CF | - | CA Osasuna | 2:0 | ||||
| 19. Ronde | 20.01.2021 | Villarreal CF | - | Granada CF | 2:2 |  |
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| 20. Ronde | 24.01.2021 | CA Osasuna | - | Granada CF | 3:1 |
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