| 1. Ronde | 23.01.2022 | Atlético Junior | - | Patriotas FC | 3:1 |  |
 |
||
| 5. Ronde | 08.02.2022 | Atlético Junior | - | Águilas Doradas | 2:1 | |
|||
| 6. Ronde | 13.02.2022 | Once Caldas | - | Atlético Junior | 1:0 | ||||
| 7. Ronde | 17.02.2022 | Independiente Medellín | - | Atlético Junior | 2:0 | ||||
| 8. Ronde | 21.02.2022 | Atlético Junior | - | América de Cali | 1:0 | |
|||
| 9. Ronde | 27.02.2022 | Deportes Tolima | - | Atlético Junior | 0:2 | |
|
||
| 10. Ronde | 05.03.2022 | Atlético Junior | - | Unión Magdalena | 3:1 | |
|||
| 13. Ronde | 31.03.2022 | Millonarios | - | Atlético Junior | 1:0 | ||||
| 14. Ronde | 03.04.2022 | Atlético Junior | - | Alianza Petrolera | 3:1 | |
|||
| 15. Ronde | 10.04.2022 | Deportivo Cali | - | Atlético Junior | 1:1 | |
|
||
| 16. Ronde | 17.04.2022 | Atlético Junior | - | Atlético Bucaramanga | 2:0 | |
|
Colombia