| 6. Ronde | 21.09.2021 | Athletic Club | - | Rayo Vallecano | 1:2 |  |
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| 11. Ronde | 26.10.2021 | Espanyol | - | Athletic Club | 1:1 | ||||
| 12. Ronde | 31.10.2021 | Real Sociedad | - | Athletic Club | 1:1 | ||||
| 13. Ronde | 05.11.2021 | Athletic Club | - | Cádiz CF | 0:1 | ||||
| 9. Ronde | 01.12.2021 | Real Madrid | - | Athletic Club | 1:0 | ||||
| 18. Ronde | 19.12.2021 | Athletic Club | - | Real Betis | 3:2 | ||||
| 21. Ronde | 22.12.2021 | Athletic Club | - | Real Madrid | 1:2 | ||||
| 24. Ronde | 14.02.2022 | RCD Mallorca | - | Athletic Club | 3:2 | ||||
| 30. Ronde | 03.04.2022 | Athletic Club | - | Elche CF | 2:1 | |
Spanje