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| 04.12.2022 | 11:30 | Real Betis B | - | Atlético Sanluqueño CF | 0:0 (0:0) | |
| 12:00 | Utrera CD | - | Sevilla Atlético | 0:4 (0:2) | ||
| 12:00 | CD San Roque | - | Cádiz CF B | 1:1 (0:0) | ||
| 12:00 | Juventud Torremolinos | - | FC Cartagena B | 1:2 (1:0) | ||
| 12:00 | UCAM Murcia CF | - | CD El Ejido 2012 | 1:1 (0:0) | ||
| 12:00 | Vélez CF | - | Mar Menor CF | 2:2 (1:1) | ||
| 12:00 | Xerez DFC | - | Recreativo Huelva | 0:1 (0:1) | ||
| 17:00 | Yeclano Deportivo | - | Antequera CF | 0:0 (0:0) | ||
| 17:45 | Atlético Mancha Real | - | Recreativo Granada | 0:1 (0:1) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Antequera CF | 13 | 9 | 3 | 1 | 24:10 | 14 | 30 |
| 2 |
|
Recreativo Huelva | 13 | 7 | 4 | 2 | 14:11 | 3 | 25 |
| 3 |
|
Yeclano Deportivo | 13 | 6 | 5 | 2 | 17:11 | 6 | 23 |
| 4 |
|
Mar Menor CF | 13 | 6 | 4 | 3 | 18:13 | 5 | 22 |
| 5 |
|
Real Betis B | 13 | 5 | 5 | 3 | 12:10 | 2 | 20 |
| 6 |
|
Atlético Sanluqueño CF | 13 | 5 | 5 | 3 | 15:14 | 1 | 20 |
| 7 |
|
FC Cartagena B | 13 | 6 | 2 | 5 | 14:13 | 1 | 20 |
| 8 |
|
Cádiz CF B | 13 | 5 | 4 | 4 | 17:14 | 3 | 19 |
| 9 |
|
Vélez CF | 13 | 5 | 3 | 5 | 15:15 | 0 | 18 |
| 10 |
|
UCAM Murcia CF | 13 | 4 | 5 | 4 | 17:15 | 2 | 17 |
| 11 |
|
Atlético Mancha Real | 13 | 4 | 4 | 5 | 9:12 | -3 | 16 |
| 12 |
|
CD San Roque | 13 | 4 | 3 | 6 | 15:15 | 0 | 15 |
| 13 |
|
CD El Ejido 2012 | 13 | 4 | 2 | 7 | 10:14 | -4 | 14 |
| 14 |
|
Recreativo Granada | 13 | 3 | 3 | 7 | 14:20 | -6 | 12 |
| 15 |
|
Xerez DFC | 13 | 2 | 6 | 5 | 8:14 | -6 | 12 |
| 16 |
|
Utrera CD | 13 | 3 | 3 | 7 | 12:21 | -9 | 12 |
| 17 |
|
Sevilla Atlético | 13 | 3 | 2 | 8 | 15:17 | -2 | 11 |
| 18 |
|
Juventud Torremolinos | 13 | 1 | 7 | 5 | 8:15 | -7 | 10 |
| Promotie | |
| Play-offs | |
| Degradatie |
