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| 08.04.2023 | 16:00 | Atlético San Luis | - | Deportivo Guadalajara | 1:1 (0:0) | |
| 16:00 | Cruz Azul | - | FC Juárez | 3:1 (2:0) | ||
| 16:00 | Gallos Blancos | - | Deportivo Toluca | 0:3 (0:2) | ||
| 18:30 | Club Necaxa | - | CF Pachuca | 6:1 (4:0) | ||
| 19:30 | Mazatlán FC | - | Santos Laguna | 2:0 (2:0) | ||
| 19.04.2023 | 17:00 | CF Monterrey | - | UANL Tigres | 1:0 (0:0) | |
| 18:00 | Pumas UNAM | - | CF América | 2:1 (1:0) | ||
| 25.04.2023 | 17:00 | Atlas Guadalajara | - | Club León | 3:2 (3:1) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| 1 | |||||||||
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Pumas UNAM | 13 | 9 | 3 | 1 | 24:10 | 14 | 30 |
| 2 |
|
CF Pachuca | 13 | 9 | 1 | 3 | 27:19 | 8 | 28 |
| 3 |
|
Club Necaxa | 12 | 5 | 5 | 2 | 31:23 | 8 | 20 |
| 4 |
|
FC Juárez | 13 | 5 | 4 | 4 | 20:19 | 1 | 19 |
| 5 |
|
CF América | 12 | 5 | 2 | 5 | 27:22 | 5 | 17 |
| 6 |
|
Deportivo Toluca | 12 | 4 | 1 | 7 | 13:21 | -8 | 13 |
| 7 |
|
Cruz Azul | 12 | 3 | 3 | 6 | 15:22 | -7 | 12 |
| 8 |
|
Puebla FC | 12 | 2 | 4 | 6 | 18:25 | -7 | 10 |
| 9 |
|
Gallos Blancos | 13 | 1 | 3 | 9 | 14:28 | -14 | 6 |
| 2 | |||||||||
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Santos Laguna | 12 | 9 | 1 | 2 | 19:9 | 10 | 28 |
| 2 |
|
CF Monterrey | 12 | 6 | 2 | 4 | 27:17 | 10 | 20 |
| 3 |
|
Deportivo Guadalajara | 13 | 5 | 4 | 4 | 19:18 | 1 | 19 |
| 4 |
|
Mazatlán FC | 12 | 5 | 4 | 3 | 17:15 | 2 | 19 |
| 5 |
|
UANL Tigres | 13 | 5 | 3 | 5 | 19:22 | -3 | 18 |
| 6 |
|
Club León | 13 | 5 | 2 | 6 | 19:22 | -3 | 17 |
| 7 |
|
Atlas Guadalajara | 13 | 5 | 2 | 6 | 22:25 | -3 | 17 |
| 8 |
|
Club Tijuana | 12 | 2 | 3 | 7 | 14:19 | -5 | 9 |
| 9 |
|
Atlético San Luis | 12 | 2 | 3 | 7 | 15:24 | -9 | 9 |
| Play-offs | |
| Play-offs |
