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| 15.04.2023 | 16:00 | Club León | - | CF Monterrey | 0:0 (0:0) | |
| 16:00 | Puebla FC | - | Cruz Azul | 0:0 (0:0) | ||
| 16:00 | Santos Laguna | - | Deportivo Guadalajara | 2:0 (1:0) | ||
| 16:00 | UANL Tigres | - | Mazatlán FC | 1:2 (1:1) | ||
| 16:00 | Deportivo Toluca | - | FC Juárez | 2:1 (1:0) | ||
| 18:30 | Club Necaxa | - | Pumas UNAM | 2:2 (1:2) | ||
| 19:00 | Club Tijuana | - | Atlético San Luis | 2:4 (2:1) | ||
| 23:00 | CF América | - | Gallos Blancos | 5:2 (3:2) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| 1 | |||||||||
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Pumas UNAM | 14 | 9 | 4 | 1 | 26:12 | 14 | 31 |
| 2 |
|
CF Pachuca | 13 | 9 | 1 | 3 | 27:19 | 8 | 28 |
| 3 |
|
Club Necaxa | 13 | 5 | 6 | 2 | 33:25 | 8 | 21 |
| 4 |
|
CF América | 13 | 6 | 2 | 5 | 32:24 | 8 | 20 |
| 5 |
|
FC Juárez | 14 | 5 | 4 | 5 | 21:21 | 0 | 19 |
| 6 |
|
Deportivo Toluca | 13 | 5 | 1 | 7 | 15:22 | -7 | 16 |
| 7 |
|
Cruz Azul | 13 | 3 | 4 | 6 | 15:22 | -7 | 13 |
| 8 |
|
Puebla FC | 13 | 2 | 5 | 6 | 18:25 | -7 | 11 |
| 9 |
|
Gallos Blancos | 14 | 1 | 3 | 10 | 16:33 | -17 | 6 |
| 2 | |||||||||
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Santos Laguna | 13 | 10 | 1 | 2 | 21:9 | 12 | 31 |
| 2 |
|
Mazatlán FC | 13 | 6 | 4 | 3 | 19:16 | 3 | 22 |
| 3 |
|
CF Monterrey | 13 | 6 | 3 | 4 | 27:17 | 10 | 21 |
| 4 |
|
Deportivo Guadalajara | 14 | 5 | 4 | 5 | 19:20 | -1 | 19 |
| 5 |
|
Club León | 14 | 5 | 3 | 6 | 19:22 | -3 | 18 |
| 6 |
|
UANL Tigres | 14 | 5 | 3 | 6 | 20:24 | -4 | 18 |
| 7 |
|
Atlas Guadalajara | 13 | 5 | 2 | 6 | 22:25 | -3 | 17 |
| 8 |
|
Atlético San Luis | 13 | 3 | 3 | 7 | 19:26 | -7 | 12 |
| 9 |
|
Club Tijuana | 13 | 2 | 3 | 8 | 16:23 | -7 | 9 |
| Play-offs | |
| Play-offs |
