 |
 |
|
| U | Cruz Azul | - | Santos Laguna | 2:1 (0:0) | ||
| R | Santos Laguna | - | Cruz Azul | 3:0 (2:0) | ||
| U: 02.12.2021 18:00 | R: 05.12.2021 18:00 | Winnaars: Santos Laguna | ||||
|
|
|
| U | Cruz Azul | - | Santos Laguna | 2:1 (0:0) | ||
| R | Santos Laguna | - | Cruz Azul | 3:0 (2:0) | ||
| U: 02.12.2021 18:00 | R: 05.12.2021 18:00 | Winnaars: Santos Laguna | ||||
