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| 04.04.2008 | 20:00 | SC Cambuur | - | ADO Den Haag | 2:1 (1:0) | |
| 20:00 | FC Emmen | - | FC Dordrecht | 1:0 (1:0) | ||
| 20:00 | Stormvogels Telstar | - | FC Omniworld | 0:1 (0:0) | ||
| 20:00 | Helmond Sport | - | Fortuna Sittard | 1:1 (1:0) | ||
| 20:00 | RKC Waalwijk | - | FC Zwolle | 2:0 (1:0) | ||
| 20:00 | MVV Maastricht | - | FC Eindhoven | 4:1 (0:1) | ||
| 20:00 | Go Ahead Eagles | - | BV Veendam | 0:1 (0:1) | ||
| 20:00 | AGOVV | - | FC Volendam | 3:6 (2:1) | ||
| 20:00 | FC Den Bosch | - | RBC Roosendaal | 2:0 (1:0) | ||
| 20:00 | TOP Oss | - | HFC Haarlem | 4:1 (3:0) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FC Volendam | 36 | 20 | 11 | 5 | 87:46 | 41 | 71 |
| 2 |
|
RKC Waalwijk | 36 | 20 | 11 | 5 | 81:43 | 38 | 71 |
| 3 |
|
FC Den Bosch | 36 | 20 | 7 | 9 | 58:36 | 22 | 67 |
| 4 |
|
FC Zwolle | 36 | 17 | 12 | 7 | 67:41 | 26 | 63 |
| 5 |
|
MVV Maastricht | 36 | 16 | 10 | 10 | 64:48 | 16 | 58 |
| 6 |
|
Helmond Sport | 36 | 17 | 7 | 12 | 52:45 | 7 | 58 |
| 7 |
|
ADO Den Haag | 36 | 16 | 9 | 11 | 56:47 | 9 | 57 |
| 8 |
|
RBC Roosendaal | 36 | 13 | 10 | 13 | 45:46 | -1 | 49 |
| 9 |
|
TOP Oss | 36 | 13 | 10 | 13 | 54:60 | -6 | 49 |
| 10 |
|
FC Emmen | 36 | 13 | 10 | 13 | 57:71 | -14 | 49 |
| 11 |
|
FC Omniworld | 36 | 11 | 14 | 11 | 55:46 | 9 | 47 |
| 12 |
|
Go Ahead Eagles | 36 | 15 | 2 | 19 | 53:61 | -8 | 47 |
| 13 |
|
FC Dordrecht | 36 | 11 | 11 | 14 | 58:50 | 8 | 44 |
| 14 |
|
BV Veendam | 36 | 11 | 14 | 11 | 55:63 | -8 | 44 |
| 15 |
|
Stormvogels Telstar | 36 | 13 | 4 | 19 | 39:47 | -8 | 43 |
| 16 |
|
Fortuna Sittard | 36 | 10 | 9 | 17 | 45:65 | -20 | 39 |
| 17 |
|
SC Cambuur | 36 | 9 | 8 | 19 | 43:65 | -22 | 35 |
| 18 |
|
AGOVV | 36 | 11 | 5 | 20 | 60:93 | -33 | 35 |
| 19 |
|
FC Eindhoven | 36 | 7 | 8 | 21 | 44:79 | -35 | 29 |
| 20 |
|
HFC Haarlem | 36 | 5 | 12 | 19 | 36:57 | -21 | 27 |
| Promotie |
