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| 19.12.2008 | 20:00 | SC Cambuur | - | Go Ahead Eagles | 2:2 (0:0) | |
| 20:00 | RKC Waalwijk | - | FC Omniworld | 1:0 (1:0) | ||
| 20:00 | Helmond Sport | - | Telstar | 1:1 (1:1) | ||
| 20:00 | FC Zwolle | - | FC Dordrecht | 2:1 (1:0) | ||
| 20:00 | RBC Roosendaal | - | Fortuna Sittard | 0:1 (0:0) | ||
| 20:00 | TOP Oss | - | FC Eindhoven | 1:2 (0:0) | ||
| 20:00 | BV Veendam | - | FC Den Bosch | 2:4 (1:2) | ||
| 20:00 | HFC Haarlem | - | AGOVV | 1:0 (1:0) | ||
| 20:00 | SBV Excelsior | - | VVV-Venlo | 1:2 (1:2) | ||
| 19.01.2009 | 20:00 | MVV Maastricht | - | FC Emmen | 1:1 (0:1) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
VVV-Venlo | 21 | 15 | 3 | 3 | 50:21 | 29 | 48 |
| 2 |
|
RKC Waalwijk | 21 | 9 | 11 | 1 | 33:19 | 14 | 38 |
| 3 |
|
SBV Excelsior | 21 | 10 | 6 | 5 | 33:21 | 12 | 36 |
| 4 |
|
SC Cambuur | 21 | 10 | 5 | 6 | 40:32 | 8 | 35 |
| 5 |
|
MVV Maastricht | 21 | 9 | 7 | 5 | 34:23 | 11 | 34 |
| 6 |
|
Helmond Sport | 21 | 8 | 8 | 5 | 32:26 | 6 | 32 |
| 7 |
|
HFC Haarlem | 21 | 10 | 2 | 9 | 28:33 | -5 | 32 |
| 8 |
|
FC Den Bosch | 21 | 8 | 7 | 6 | 37:28 | 9 | 31 |
| 9 |
|
FC Zwolle | 21 | 8 | 7 | 6 | 35:32 | 3 | 31 |
| 10 |
|
Go Ahead Eagles | 21 | 7 | 8 | 6 | 21:26 | -5 | 29 |
| 11 |
|
AGOVV | 21 | 8 | 3 | 10 | 31:38 | -7 | 27 |
| 12 |
|
RBC Roosendaal | 21 | 6 | 7 | 8 | 26:26 | 0 | 25 |
| 13 |
|
Fortuna Sittard | 21 | 6 | 6 | 9 | 23:35 | -12 | 24 |
| 14 |
|
Telstar | 21 | 5 | 8 | 8 | 28:33 | -5 | 23 |
| 15 |
|
TOP Oss | 21 | 6 | 5 | 10 | 25:34 | -9 | 23 |
| 16 |
|
FC Eindhoven | 21 | 5 | 10 | 6 | 36:39 | -3 | 22 |
| 17 |
|
FC Emmen | 21 | 5 | 6 | 10 | 27:42 | -15 | 21 |
| 18 |
|
BV Veendam | 21 | 5 | 8 | 8 | 26:35 | -9 | 20 |
| 19 |
|
FC Dordrecht | 21 | 3 | 6 | 12 | 19:26 | -7 | 15 |
| 20 |
|
FC Omniworld | 21 | 3 | 5 | 13 | 22:37 | -15 | 14 |
| Promotie | |
| Play-offs | |
| Play-offs | |
| Play-offs | |
| Play-offs |
