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| 27.11.2009 | De Graafschap | - | HFC Haarlem | geannuleerd | ||
| 19:30 | FC Zwolle | - | SC Cambuur | 1:0 (1:0) | ||
| 20:00 | FC Emmen | - | FC Eindhoven | 4:1 (1:1) | ||
| 20:00 | TOP Oss | - | SBV Excelsior | 1:2 (0:1) | ||
| 20:00 | Telstar | - | Fortuna Sittard | 3:1 (0:1) | ||
| 20:00 | MVV Maastricht | - | AGOVV | 3:2 (1:1) | ||
| 20:00 | FC Dordrecht | - | Go Ahead Eagles | 2:0 (0:0) | ||
| 20:00 | FC Omniworld | - | BV Veendam | 1:1 (1:1) | ||
| 20:00 | RBC Roosendaal | - | FC Volendam | 2:2 (0:0) | ||
| 20:00 | Helmond Sport | - | FC Den Bosch | 2:1 (1:1) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Go Ahead Eagles | 17 | 11 | 3 | 3 | 31:12 | 19 | 36 |
| 2 |
|
De Graafschap | 17 | 10 | 5 | 2 | 32:13 | 19 | 35 |
| 3 |
|
SC Cambuur | 17 | 10 | 5 | 2 | 40:28 | 12 | 35 |
| 4 |
|
SBV Excelsior | 17 | 9 | 4 | 4 | 30:23 | 7 | 31 |
| 5 |
|
FC Zwolle | 18 | 8 | 5 | 5 | 25:22 | 3 | 29 |
| 6 |
|
FC Den Bosch | 17 | 7 | 7 | 3 | 36:23 | 13 | 28 |
| 7 |
|
Helmond Sport | 17 | 8 | 4 | 5 | 35:28 | 7 | 28 |
| 8 |
|
FC Dordrecht | 17 | 8 | 2 | 7 | 36:24 | 12 | 26 |
| 9 |
|
MVV Maastricht | 17 | 8 | 2 | 7 | 32:34 | -2 | 25 |
| 10 |
|
AGOVV | 17 | 7 | 5 | 5 | 33:28 | 5 | 24 |
| 11 |
|
BV Veendam | 17 | 6 | 6 | 5 | 27:22 | 5 | 23 |
| 12 |
|
RBC Roosendaal | 17 | 5 | 5 | 7 | 18:22 | -4 | 20 |
| 13 |
|
Telstar | 17 | 5 | 4 | 8 | 26:28 | -2 | 19 |
| 14 |
|
FC Volendam | 17 | 4 | 6 | 7 | 30:38 | -8 | 18 |
| 15 |
|
FC Emmen | 17 | 4 | 3 | 10 | 19:36 | -17 | 15 |
| 16 |
|
FC Eindhoven | 17 | 3 | 5 | 9 | 27:46 | -19 | 14 |
| 17 |
|
TOP Oss | 17 | 3 | 3 | 11 | 22:37 | -15 | 12 |
| 18 |
|
FC Omniworld | 17 | 3 | 3 | 11 | 15:30 | -15 | 12 |
| 19 |
|
Fortuna Sittard | 17 | 2 | 5 | 10 | 13:33 | -20 | 11 |
| 20 |
|
HFC Haarlem | 0 | 0 | 0 | 0 | 0:0 | 0 | 0 |
| Promotie | |
| Play-offs | |
| Play-offs |
