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| 02.04.2010 | 20:00 | BV Veendam | - | SBV Excelsior | 2:1 (1:1) | |
| 20:00 | FC Den Bosch | - | FC Emmen | 4:4 (2:0) | ||
| 20:00 | MVV Maastricht | - | SC Cambuur | 2:1 (1:1) | ||
| 20:00 | RBC Roosendaal | - | AGOVV | 0:2 (0:1) | ||
| 20:00 | Helmond Sport | - | Telstar | 0:1 (0:0) | ||
| 20:00 | FC Volendam | - | FC Eindhoven | 0:2 (0:1) | ||
| 20:00 | FC Zwolle | - | TOP Oss | 0:0 (0:0) | ||
| 04.04.2010 | 12:30 | De Graafschap | - | Go Ahead Eagles | 3:2 (0:2) | |
| 12.04.2010 | 20:00 | FC Omniworld | - | FC Dordrecht | 1:1 (0:0) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
De Graafschap | 33 | 23 | 6 | 4 | 71:27 | 44 | 75 |
| 2 |
|
SC Cambuur | 33 | 19 | 8 | 6 | 75:47 | 28 | 65 |
| 3 |
|
Go Ahead Eagles | 33 | 17 | 8 | 8 | 49:29 | 20 | 59 |
| 4 |
|
SBV Excelsior | 33 | 17 | 5 | 11 | 63:45 | 18 | 56 |
| 5 |
|
FC Zwolle | 33 | 16 | 8 | 9 | 49:35 | 14 | 56 |
| 6 |
|
FC Den Bosch | 34 | 14 | 12 | 8 | 65:48 | 17 | 54 |
| 7 |
|
AGOVV | 33 | 15 | 9 | 9 | 58:46 | 12 | 52 |
| 8 |
|
Helmond Sport | 33 | 14 | 6 | 13 | 60:51 | 9 | 48 |
| 9 |
|
BV Veendam | 33 | 13 | 9 | 11 | 54:46 | 8 | 47 |
| 10 |
|
RBC Roosendaal | 33 | 11 | 10 | 12 | 44:48 | -4 | 43 |
| 11 |
|
FC Eindhoven | 33 | 12 | 7 | 14 | 58:70 | -12 | 43 |
| 12 |
|
MVV Maastricht | 34 | 12 | 7 | 15 | 52:65 | -13 | 42 |
| 13 |
|
FC Omniworld | 33 | 11 | 7 | 15 | 38:52 | -14 | 40 |
| 14 |
|
FC Emmen | 34 | 10 | 8 | 16 | 51:74 | -23 | 38 |
| 15 |
|
FC Dordrecht | 33 | 11 | 4 | 18 | 49:56 | -7 | 37 |
| 16 |
|
FC Volendam | 33 | 7 | 11 | 15 | 54:74 | -20 | 32 |
| 17 |
|
Telstar | 33 | 7 | 6 | 20 | 42:61 | -19 | 27 |
| 18 |
|
Fortuna Sittard | 33 | 6 | 9 | 18 | 29:53 | -24 | 27 |
| 19 |
|
TOP Oss | 33 | 5 | 10 | 18 | 39:73 | -34 | 25 |
| 20 |
|
HFC Haarlem | 0 | 0 | 0 | 0 | 0:0 | 0 | 0 |
| Promotie | |
| Play-offs | |
| Play-offs |
