| 1. Ronde | 09.01.2022 | Santos Laguna [] | - | CF Monterrey [] | 2:1 | ||||
| 6. Ronde | 12.02.2022 | UANL Tigres [] | - | CF Monterrey [] | 1:0 | ||||
| 7. Ronde | 19.02.2022 | Club Tijuana [] | - | CF Monterrey [] | 1:1 | ||||
| 8. Ronde | 26.02.2022 | CF Monterrey [] | - | Atlético San Luis [] | 7:0 | ||||
| 10. Ronde | 12.03.2022 | Mazatlán FC [] | - | CF Monterrey [] | 1:3 | ||||
| 15. Ronde | 30.03.2022 | Deportivo Guadalajara [] | - | CF Monterrey [] | 4:1 | ||||
| 17. Ronde | 30.04.2022 | Club León [] | - | CF Monterrey [] | 1:1 | ||||
| 18. Ronde | 07.05.2022 | CF Monterrey [] | - | Club Tijuana [] | 1:0 |
Mexico