| 1. Ronde | 16.07.2021 | Vélez Sarsfield II | - | Racing Club II | 1:1 | ||||
| 2. Ronde | 23.07.2021 | Rosario Central II | - | Vélez Sarsfield II | 3:0 | ||||
| 3. Ronde | 26.07.2021 | Vélez Sarsfield II | - | Defensa y Justicia II | 0:0 | ||||
| 5. Ronde | 06.08.2021 | Vélez Sarsfield II | - | Colón de Santa Fe II | 0:2 | ||||
| 6. Ronde | 13.08.2021 | River Plate II | - | Vélez Sarsfield II | 1:2 | ||||
| 7. Ronde | 20.08.2021 | Vélez Sarsfield II | - | Lanús II | 1:0 | ||||
| 8. Ronde | 25.08.2021 | Huracán II | - | Vélez Sarsfield II | 2:2 | ||||
| 11. Ronde | 10.09.2021 | Gimnasia de La Plata II | - | Vélez Sarsfield II | 2:3 | ||||
| 13. Ronde | 24.09.2021 | Sarmiento de Junín II | - | Vélez Sarsfield II | 0:4 | ||||
| 14. Ronde | 01.10.2021 | Vélez Sarsfield II | - | Independiente II | 0:0 | ||||
| 15. Ronde | 08.10.2021 | Newell's Old Boys II | - | Vélez Sarsfield II | 0:0 | ||||
| 17. Ronde | 19.10.2021 | Central Córdoba SdE II | - | Vélez Sarsfield II | 2:0 | ||||
| 19. Ronde | 29.10.2021 | Banfield II | - | Vélez Sarsfield II | 1:2 | ||||
| 9. Ronde | 11.11.2021 | Vélez Sarsfield II | - | Godoy Cruz II | 3:0 |  |
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| 23. Ronde | 29.11.2021 | Estudiantes II | - | Vélez Sarsfield II | 2:3 | ||||
| 25. Ronde | 09.12.2021 | Platense II | - | Vélez Sarsfield II | 3:1 |
Argentinië