| 1. Ronde | 07.08.2021 | Andrézieux-Bouthéon FC | - | Angers SCO B | 3:1 |  |
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| 2. Ronde | 14.08.2021 | Angers SCO B | - | US Colomiers | 0:0 | ||||
| 4. Ronde | 28.08.2021 | Angers SCO B | - | Canet Roussillon | 2:0 | ||||
| 5. Ronde | 03.09.2021 | Angoulême CFC | - | Angers SCO B | 4:0 | |
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| 6. Ronde | 11.09.2021 | Angers SCO B | - | Trélissac FC | 0:1 | ||||
| 8. Ronde | 25.09.2021 | Angers SCO B | - | AS Béziers | 2:0 | ||||
| 12. Ronde | 20.11.2021 | Bergerac Périgord FC | - | Angers SCO B | 2:1 | ||||
| 15. Ronde | 15.01.2022 | Angers SCO B | - | FC Chamalières | 1:1 | ||||
| 16. Ronde | 22.01.2022 | US Colomiers | - | Angers SCO B | 0:0 | ||||
| 19. Ronde | 19.02.2022 | Angers SCO B | - | Angoulême CFC | 0:0 | ||||
| 22. Ronde | 19.03.2022 | AS Béziers | - | Angers SCO B | 1:1 |  |
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| 23. Ronde | 26.03.2022 | Angers SCO B | - | Stade Montois | 0:0 | ||||
| 25. Ronde | 16.04.2022 | Angers SCO B | - | Le Puy Foot 43 | 0:2 | ||||
| 26. Ronde | 23.04.2022 | Angers SCO B | - | Bergerac Périgord FC | 0:1 | ||||
| 27. Ronde | 29.04.2022 | Vendée Les Herbiers | - | Angers SCO B | 1:1 | ||||
| 28. Ronde | 14.05.2022 | Angers SCO B | - | Montpellier HSC B | 1:0 |
Frankrijk
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