| 2. Ronde | 24.07.2021 | Atlético Tucumán | - | Huracán | 1:0 | ||||
| 3. Ronde | 28.07.2021 | Godoy Cruz | - | Atlético Tucumán | 1:2 | ||||
| 8. Ronde | 24.08.2021 | Atlético Tucumán | - | Independiente | 2:0 | ||||
| 9. Ronde | 30.08.2021 | Newell's Old Boys | - | Atlético Tucumán | 1:2 |  |
|||
| 10. Ronde | 04.09.2021 | Atlético Tucumán | - | Arsenal de Sarandí | 0:0 | ||||
| 12. Ronde | 19.09.2021 | Atlético Tucumán | - | Boca Juniors | 1:2 | ||||
| 13. Ronde | 25.09.2021 | Banfield | - | Atlético Tucumán | 2:0 | ||||
| 14. Ronde | 02.10.2021 | Atlético Tucumán | - | San Lorenzo | 0:0 | ||||
| 15. Ronde | 12.10.2021 | Talleres de Córdoba | - | Atlético Tucumán | 2:0 | ||||
| 16. Ronde | 17.10.2021 | Atlético Tucumán | - | Argentinos Juniors | 4:3 | ||||
| 17. Ronde | 21.10.2021 | Estudiantes | - | Atlético Tucumán | 1:1 | |
|||
| 18. Ronde | 25.10.2021 | Atlético Tucumán | - | Patronato de Paraná | 2:2 | ||||
| 19. Ronde | 30.10.2021 | Platense | - | Atlético Tucumán | 4:1 | |
|||
| 22. Ronde | 24.11.2021 | Atlético Tucumán | - | Defensa y Justicia | 0:4 | ||||
| 23. Ronde | 29.11.2021 | Unión de Santa Fe | - | Atlético Tucumán | 3:0 | |
|||
| 24. Ronde | 03.12.2021 | Colón de Santa Fe | - | Atlético Tucumán | 3:0 | ||||
| 25. Ronde | 11.12.2021 | Atlético Tucumán | - | River Plate | 1:1 |  |
Argentinië