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| 22.10.2021 | 20:00 | Argentino de Quilmes | - | Sacachispas | 0:0 (0:0) | |
| 23.10.2021 | 18:10 | Colegiales de Munro | - | Cañuelas | 2:0 (1:0) | |
| 20:00 | Comunicaciones de Buenos Aires | - | UAI Urquiza | 2:0 (0:0) | ||
| 20:00 | Armenio | - | Talleres (RdE) | 1:3 (0:2) | ||
| 20:00 | Fénix | - | Flandria | 0:4 (0:1) | ||
| 20:30 | CA Los Andes | - | Acassuso | 0:1 (0:1) | ||
| 24.10.2021 | 20:00 | Defensores Unidos de Zárate | - | Deportivo Merlo | 2:1 (1:1) | |
| 20:00 | Villa San Carlos | - | Atlético San Miguel | 4:2 (3:0) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Colegiales de Munro | 14 | 9 | 2 | 3 | 22:9 | 13 | 29 |
| 2 |
|
Flandria | 14 | 8 | 4 | 2 | 32:12 | 20 | 28 |
| 3 |
|
Acassuso | 14 | 6 | 6 | 2 | 15:8 | 7 | 24 |
| 4 |
|
Sacachispas | 14 | 5 | 8 | 1 | 20:8 | 12 | 23 |
| 5 |
|
Justo José de Urquiza | 14 | 6 | 3 | 5 | 19:18 | 1 | 21 |
| 6 |
|
CA Los Andes | 14 | 4 | 8 | 2 | 16:10 | 6 | 20 |
| 7 |
|
Cañuelas | 14 | 5 | 5 | 4 | 17:14 | 3 | 20 |
| 8 |
|
Comunicaciones de Buenos Aires | 14 | 5 | 3 | 6 | 15:19 | -4 | 18 |
| 9 |
|
Defensores Unidos de Zárate | 14 | 4 | 6 | 4 | 12:17 | -5 | 18 |
| 10 |
|
Armenio | 14 | 4 | 5 | 5 | 11:16 | -5 | 17 |
| 11 |
|
UAI Urquiza | 15 | 3 | 7 | 5 | 17:23 | -6 | 16 |
| 12 |
|
Atlético San Miguel | 14 | 4 | 4 | 6 | 14:22 | -8 | 16 |
| 13 |
|
Talleres (RdE) | 14 | 2 | 9 | 3 | 13:13 | 0 | 15 |
| 14 |
|
Villa San Carlos | 14 | 3 | 6 | 5 | 15:21 | -6 | 15 |
| 15 |
|
Argentino de Quilmes | 15 | 1 | 10 | 4 | 15:25 | -10 | 13 |
| 16 |
|
Deportivo Merlo | 14 | 2 | 4 | 8 | 11:17 | -6 | 10 |
| 17 |
|
Fénix | 14 | 1 | 6 | 7 | 8:20 | -12 | 9 |
| Volgende Ronde |
