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| 04.08.2022 | 15:00 | Racing Club II | - | Barracas Central II | 1:1 (0:0) | |
| 16:00 | Huracán II | - | Aldosivi II | 4:1 (2:1) | ||
| 16:00 | Lanús II | - | Sarmiento de Junín II | 4:0 (2:0) | ||
| 16:00 | Patronato de Paraná II | - | Banfield II | 2:0 (0:0) | ||
| 05.08.2022 | 15:00 | Platense II | - | Boca Juniors II | 0:0 (0:0) | |
| 16:00 | Vélez Sarsfield II | - | Unión de Santa Fe II | 0:0 (0:0) | ||
| 16:00 | Atlético Tucumán II | - | Arsenal de Sarandí II | 1:4 (0:1) | ||
| 16:00 | Defensa y Justicia II | - | Central Córdoba SdE II | 1:0 (0:0) | ||
| 06.08.2022 | 15:00 | River Plate II | - | Independiente II | 2:1 (1:0) | |
| 15:00 | Colón de Santa Fe II | - | Newell's Old Boys II | 0:2 (0:1) | ||
| 15:00 | Rosario Central II | - | Tigre II | 2:0 (0:0) | ||
| 07.08.2022 | 15:00 | Godoy Cruz II | - | Gimnasia de La Plata II | 1:1 (0:0) | |
| 15:00 | Argentinos Juniors II | - | Talleres de Córdoba II | 3:1 (1:0) | ||
| 08.08.2022 | 15:00 | Estudiantes II | - | San Lorenzo II | 4:2 (2:1) |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
River Plate II | 12 | 9 | 0 | 3 | 19:8 | 11 | 27 |
| 2 |
|
Vélez Sarsfield II | 12 | 7 | 2 | 3 | 25:8 | 17 | 23 |
| 3 |
|
Newell's Old Boys II | 12 | 6 | 5 | 1 | 17:9 | 8 | 23 |
| 4 |
|
Huracán II | 12 | 7 | 2 | 3 | 23:18 | 5 | 23 |
| 5 |
|
Boca Juniors II | 12 | 7 | 1 | 4 | 17:10 | 7 | 22 |
| 6 |
|
Rosario Central II | 12 | 6 | 3 | 3 | 24:15 | 9 | 21 |
| 7 |
|
Argentinos Juniors II | 12 | 6 | 3 | 3 | 20:13 | 7 | 21 |
| 8 |
|
Tigre II | 12 | 6 | 3 | 3 | 13:12 | 1 | 21 |
| 9 |
|
Defensa y Justicia II | 12 | 6 | 2 | 4 | 12:12 | 0 | 20 |
| 10 |
|
Gimnasia de La Plata II | 12 | 5 | 3 | 4 | 19:15 | 4 | 18 |
|
Independiente II | 12 | 5 | 3 | 4 | 19:15 | 4 | 18 | |
| 12 |
|
Central Córdoba SdE II | 12 | 5 | 3 | 4 | 12:12 | 0 | 18 |
| 13 |
|
Racing Club II | 12 | 4 | 5 | 3 | 22:12 | 10 | 17 |
| 14 |
|
Arsenal de Sarandí II | 12 | 4 | 5 | 3 | 13:9 | 4 | 17 |
| 15 |
|
Unión de Santa Fe II | 12 | 4 | 4 | 4 | 11:11 | 0 | 16 |
| 16 |
|
Atlético Tucumán II | 12 | 4 | 3 | 5 | 17:19 | -2 | 15 |
| 17 |
|
San Lorenzo II | 12 | 4 | 2 | 6 | 16:18 | -2 | 14 |
| 18 |
|
Banfield II | 12 | 4 | 2 | 6 | 10:13 | -3 | 14 |
| 19 |
|
Colón de Santa Fe II | 12 | 3 | 5 | 4 | 10:18 | -8 | 14 |
| 20 |
|
Godoy Cruz II | 12 | 3 | 4 | 5 | 13:18 | -5 | 13 |
| 21 |
|
Estudiantes II | 12 | 3 | 4 | 5 | 10:15 | -5 | 13 |
| 22 |
|
Lanús II | 12 | 4 | 1 | 7 | 20:26 | -6 | 13 |
| 23 |
|
Aldosivi II | 12 | 4 | 1 | 7 | 21:30 | -9 | 13 |
| 24 |
|
Platense II | 12 | 2 | 5 | 5 | 10:14 | -4 | 11 |
| 25 |
|
Talleres de Córdoba II | 12 | 3 | 2 | 7 | 14:20 | -6 | 11 |
| 26 |
|
Patronato de Paraná II | 12 | 3 | 2 | 7 | 10:21 | -11 | 11 |
| 27 |
|
Barracas Central II | 12 | 3 | 1 | 8 | 6:18 | -12 | 10 |
| 28 |
|
Sarmiento de Junín II | 12 | 2 | 2 | 8 | 8:22 | -14 | 8 |
