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| 13.06.2022 | 14:00 | Tigre II | - | Boca Juniors II | 0:2 (0:1) | |
| 16:00 | Unión de Santa Fe II | - | Barracas Central II | 0:1 (0:0) | ||
| 14.06.2022 | 14:00 | Arsenal de Sarandí II | - | San Lorenzo II | 0:1 (0:0) | |
| 14:00 | River Plate II | - | Colón de Santa Fe II | 0:2 (0:1) | ||
| 16:00 | Lanús II | - | Atlético Tucumán II | 2:4 (2:2) | ||
| 16:00 | Central Córdoba SdE II | - | Banfield II | 2:3 (1:2) | ||
| 16:00 | Huracán II | - | Defensa y Justicia II | 3:0 (3:0) | ||
| 15.06.2022 | 14:00 | Independiente II | - | Argentinos Juniors II | 0:3 (0:2) | |
| 14:00 | Vélez Sarsfield II | - | Racing Club II | 2:1 (0:0) | ||
| 16:00 | Aldosivi II | - | Patronato de Paraná II | 6:1 (4:0) | ||
| 16:00 | Sarmiento de Junín II | - | Estudiantes II | 0:1 (0:0) | ||
| 16:00 | Gimnasia de La Plata II | - | Platense II | 2:0 (2:0) | ||
| 16:00 | Godoy Cruz II | - | Rosario Central II | 1:1 (1:0) | ||
| 16:00 | Newell's Old Boys II | - | Talleres de Córdoba II | 0:0 (0:0) |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Aldosivi II | 3 | 2 | 1 | 0 | 10:4 | 6 | 7 |
| 2 |
|
Argentinos Juniors II | 3 | 2 | 1 | 0 | 9:3 | 6 | 7 |
| 3 |
|
Atlético Tucumán II | 3 | 2 | 1 | 0 | 7:4 | 3 | 7 |
| 4 |
|
Vélez Sarsfield II | 3 | 2 | 1 | 0 | 5:3 | 2 | 7 |
| 5 |
|
Newell's Old Boys II | 3 | 2 | 1 | 0 | 4:2 | 2 | 7 |
| 6 |
|
Racing Club II | 3 | 2 | 0 | 1 | 7:2 | 5 | 6 |
| 7 |
|
Gimnasia de La Plata II | 3 | 2 | 0 | 1 | 5:2 | 3 | 6 |
| 8 |
|
Arsenal de Sarandí II | 3 | 2 | 0 | 1 | 4:1 | 3 | 6 |
| 9 |
|
Boca Juniors II | 3 | 2 | 0 | 1 | 5:3 | 2 | 6 |
| 10 |
|
San Lorenzo II | 3 | 2 | 0 | 1 | 4:3 | 1 | 6 |
| 11 |
|
Colón de Santa Fe II | 3 | 1 | 2 | 0 | 5:3 | 2 | 5 |
| 12 |
|
Unión de Santa Fe II | 3 | 1 | 1 | 1 | 4:2 | 2 | 4 |
| 13 |
|
Godoy Cruz II | 3 | 1 | 1 | 1 | 3:3 | 0 | 4 |
| 14 |
|
Huracán II | 3 | 1 | 1 | 1 | 6:8 | -2 | 4 |
| 15 |
|
Rosario Central II | 3 | 0 | 3 | 0 | 6:6 | 0 | 3 |
| 16 |
|
Independiente II | 3 | 1 | 0 | 2 | 4:4 | 0 | 3 |
| 17 |
|
Central Córdoba SdE II | 3 | 1 | 0 | 2 | 5:6 | -1 | 3 |
| 18 |
|
River Plate II | 3 | 1 | 0 | 2 | 2:3 | -1 | 3 |
| 19 |
|
Banfield II | 3 | 1 | 0 | 2 | 3:5 | -2 | 3 |
| 20 |
|
Barracas Central II | 3 | 1 | 0 | 2 | 2:4 | -2 | 3 |
|
Estudiantes II | 3 | 1 | 0 | 2 | 2:4 | -2 | 3 | |
| 22 |
|
Tigre II | 3 | 1 | 0 | 2 | 2:6 | -4 | 3 |
| 23 |
|
Defensa y Justicia II | 3 | 1 | 0 | 2 | 1:5 | -4 | 3 |
| 24 |
|
Patronato de Paraná II | 3 | 1 | 0 | 2 | 4:9 | -5 | 3 |
| 25 |
|
Talleres de Córdoba II | 3 | 0 | 2 | 1 | 1:5 | -4 | 2 |
| 26 |
|
Lanús II | 3 | 0 | 1 | 2 | 4:7 | -3 | 1 |
| 27 |
|
Platense II | 3 | 0 | 1 | 2 | 2:5 | -3 | 1 |
| 28 |
|
Sarmiento de Junín II | 3 | 0 | 1 | 2 | 2:6 | -4 | 1 |
