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| U | Zamalek | - | Espérance de Tunis | 3:1 (1:1) | ||
| R | Espérance de Tunis | - | Zamalek | 1:0 (1:0) | ||
| U: 28.02.2020 17:00 | R: 06.03.2020 20:00 | Winnaars: Zamalek | ||||
| U | Raja Casablanca | - | TP Mazembe | 2:0 (1:0) | ||
| R | TP Mazembe | - | Raja Casablanca | 1:0 (0:0) | ||
| U: 28.02.2020 20:00 | R: 07.03.2020 14:00 | Winnaars: Raja Casablanca | ||||
| U | Al Ahly SC | - | Mamelodi Sundowns | 2:0 (0:0) | ||
| R | Mamelodi Sundowns | - | Al Ahly SC | 1:1 (1:1) | ||
| U: 29.02.2020 17:00 | R: 07.03.2020 14:00 | Winnaars: Al Ahly SC | ||||
| U | Wydad AC | - | Étoile du Sahel | 2:0 (1:0) | ||
| R | Étoile du Sahel | - | Wydad AC | 1:0 (0:0) | ||
| U: 29.02.2020 20:00 | R: 07.03.2020 20:00 | Winnaars: Wydad AC | ||||
