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| U | Palmeiras | - | Atlético Mineiro | 0:0 (0:0) | ||
| R | Atlético Mineiro | - | Palmeiras | 1:1 (0:0) | ||
| U: 22.09.2021 02:30 | R: 29.09.2021 02:30 | Winnaars: Palmeiras | ||||
| U | Flamengo RJ | - | Barcelona | 2:0 (2:0) | ||
| R | Barcelona | - | Flamengo RJ | 0:2 (0:1) | ||
| U: 23.09.2021 02:30 | R: 30.09.2021 02:30 | Winnaars: Flamengo RJ | ||||
