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| U | Dynamo České Budějovice | - | FK Mladá Boleslav | 2:3 (1:3) | ||
| R | FK Mladá Boleslav | - | Dynamo České Budějovice | 1:0 (0:0) | ||
| U: 24.04.2022 16:00 | R: 30.04.2022 16:00 | Winnaars: FK Mladá Boleslav | ||||
| U | Sigma Olomouc | - | Slovan Liberec | 1:0 (1:0) | ||
| R | Slovan Liberec | - | Sigma Olomouc | 0:2 (0:1) | ||
| U: 24.04.2022 16:00 | R: 30.04.2022 16:00 | Winnaars: Sigma Olomouc | ||||
