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| U | CD Tenerife | - | UD Las Palmas | 1:0 (1:0) | ||
| R | UD Las Palmas | - | CD Tenerife | 1:2 (0:2) | ||
| U: 01.06.2022 21:00 | R: 04.06.2022 21:00 | Winnaars: CD Tenerife | ||||
| U | Girona FC | - | SD Eibar | 0:1 (0:1) | ||
| R | SD Eibar | - | Girona FC | 0:2 (0:1, 0:1) n.v. | ||
| U: 02.06.2022 19:00 | R: 05.06.2022 18:30 | Winnaars: Girona FC | ||||
