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| 01.12.2021 | 19:00 | ESTAC Troyes | - | FC Lorient | 2:0 (2:0) | |
| 19:00 | FC Metz | - | Montpellier HSC | 1:3 (0:2) | ||
| 19:00 | RC Strasbourg | - | Girondins Bordeaux | 5:2 (3:1) | ||
| 19:00 | Angers SCO | - | AS Monaco | 1:3 (0:2) | ||
| 19:00 | Stade Brestois | - | AS Saint-Étienne | 1:0 (0:0) | ||
| 21:00 | Clermont Foot 63 | - | RC Lens | 2:2 (1:1) | ||
| 21:00 | FC Nantes | - | Olympique Marseille | 0:1 (0:1) | ||
| 21:00 | Olympique Lyon | - | Stade Reims | 1:2 (0:0) | ||
| 21:00 | Paris Saint-Germain | - | OGC Nice | 0:0 (0:0) | ||
| 21:00 | Stade Rennais | - | Lille OSC | 1:2 (0:2) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Paris Saint-Germain | 16 | 13 | 2 | 1 | 35:15 | 20 | 41 |
| 2 |
|
Olympique Marseille | 16 | 8 | 5 | 3 | 23:14 | 9 | 29 |
| 3 |
|
Stade Rennais | 16 | 8 | 4 | 4 | 27:14 | 13 | 28 |
| 4 |
|
OGC Nice | 16 | 8 | 4 | 4 | 25:12 | 13 | 27 |
| 5 |
|
RC Lens | 16 | 7 | 5 | 4 | 29:22 | 7 | 26 |
| 6 |
|
Olympique Lyon | 16 | 7 | 4 | 5 | 25:24 | 1 | 24 |
| 7 |
|
RC Strasbourg | 16 | 6 | 5 | 5 | 31:22 | 9 | 23 |
| 8 |
|
AS Monaco | 16 | 6 | 5 | 5 | 23:20 | 3 | 23 |
| 9 |
|
Angers SCO | 16 | 5 | 7 | 4 | 23:21 | 2 | 22 |
| 10 |
|
Montpellier HSC | 16 | 6 | 4 | 6 | 24:23 | 1 | 22 |
| 11 |
|
Stade Brestois | 16 | 5 | 6 | 5 | 23:22 | 1 | 21 |
| 12 |
|
Lille OSC | 16 | 5 | 6 | 5 | 21:23 | -2 | 21 |
| 13 |
|
FC Nantes | 16 | 5 | 4 | 7 | 20:21 | -1 | 19 |
| 14 |
|
Stade Reims | 16 | 4 | 7 | 5 | 18:19 | -1 | 19 |
| 15 |
|
ESTAC Troyes | 16 | 4 | 4 | 8 | 15:23 | -8 | 16 |
| 16 |
|
FC Lorient | 16 | 3 | 6 | 7 | 13:25 | -12 | 15 |
| 17 |
|
Clermont Foot 63 | 16 | 3 | 5 | 8 | 19:31 | -12 | 14 |
| 18 |
|
Girondins Bordeaux | 16 | 2 | 7 | 7 | 24:37 | -13 | 13 |
| 19 |
|
FC Metz | 16 | 2 | 6 | 8 | 18:33 | -15 | 12 |
| 20 |
|
AS Saint-Étienne | 16 | 2 | 6 | 8 | 17:32 | -15 | 12 |
| Champions League | |
| Champions League Kwali. | |
| Europa League | |
| Promotie en degradatie | |
| Degradatie |
