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| 18.01.2016 | 20:00 | Sparta Rotterdam | - | RKC Waalwijk | 5:2 (3:0) | |
| 20:00 | FC Dordrecht | - | FC Emmen | 0:2 (0:0) | ||
| 20:00 | NAC Breda | - | FC Eindhoven | 3:1 (3:0) | ||
| 20:00 | Jong PSV | - | MVV Maastricht | 2:0 (2:0) | ||
| 20:00 | FC Den Bosch | - | FC Volendam | 0:0 (0:0) | ||
| 20:00 | TOP Oss | - | VVV-Venlo | 2:1 (0:0) | ||
| 20:00 | Telstar | - | Go Ahead Eagles | 1:2 (0:1) | ||
| 20:00 | Helmond Sport | - | Jong Ajax | 2:3 (2:1) | ||
| 25.01.2016 | 20:00 | Achilles'29 | - | Fortuna Sittard | 3:0 (0:0) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Sparta Rotterdam | 19 | 14 | 3 | 2 | 51:21 | 30 | 45 |
| 2 |
|
VVV-Venlo | 20 | 12 | 4 | 4 | 45:17 | 28 | 40 |
| 3 |
|
NAC Breda | 20 | 12 | 3 | 5 | 44:20 | 24 | 39 |
| 4 |
|
Go Ahead Eagles | 20 | 11 | 1 | 8 | 35:25 | 10 | 34 |
| 5 |
|
FC Eindhoven | 20 | 10 | 4 | 6 | 31:26 | 5 | 34 |
| 6 |
|
FC Volendam | 20 | 9 | 5 | 6 | 34:20 | 14 | 32 |
| 7 |
|
FC Emmen | 20 | 8 | 4 | 8 | 35:33 | 2 | 28 |
| 8 |
|
Helmond Sport | 20 | 7 | 6 | 7 | 34:31 | 3 | 27 |
| 9 |
|
Jong Ajax | 20 | 7 | 6 | 7 | 33:34 | -1 | 27 |
| 10 |
|
FC Den Bosch | 20 | 6 | 8 | 6 | 26:27 | -1 | 26 |
| 11 |
|
FC Dordrecht | 20 | 7 | 4 | 9 | 27:33 | -6 | 25 |
| 12 |
|
MVV Maastricht | 20 | 7 | 4 | 9 | 32:40 | -8 | 25 |
| 13 |
|
TOP Oss | 20 | 6 | 6 | 8 | 25:33 | -8 | 24 |
| 14 |
|
Jong PSV | 20 | 6 | 6 | 8 | 27:41 | -14 | 24 |
| 15 |
|
Achilles'29 | 20 | 6 | 5 | 9 | 24:31 | -7 | 23 |
| 16 |
|
Telstar | 20 | 5 | 5 | 10 | 28:37 | -9 | 20 |
| 17 |
|
Fortuna Sittard | 20 | 5 | 4 | 11 | 22:49 | -27 | 19 |
| 18 |
|
RKC Waalwijk | 20 | 4 | 5 | 11 | 21:39 | -18 | 17 |
| 19 |
|
Almere City FC | 19 | 3 | 5 | 11 | 28:45 | -17 | 14 |
| Promotie | |
| Play-offs | |
| Play-offs | |
| Play-offs |
