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|
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| 26.11.2021 | 20:00 | ADO Den Haag | - | FC Dordrecht | 5:1 (4:0) | |
| 20:00 | De Graafschap | - | Jong Ajax | 1:3 (1:1) | ||
| 20:00 | FC Eindhoven | - | Jong AZ Alkmaar | 1:0 (1:0) | ||
| 20:00 | SBV Excelsior | - | Jong FC Utrecht | 2:1 (0:1) | ||
| 20:00 | TOP Oss | - | Telstar | 1:1 (1:0) | ||
| 20:00 | FC Volendam | - | FC Den Bosch | 3:0 (1:0) | ||
| 20:00 | MVV Maastricht | - | Jong PSV | 1:2 (1:0) | ||
| 20:00 | Roda JC Kerkrade | - | VVV-Venlo | 0:0 (0:0) | ||
| 27.11.2021 | 16:30 | NAC Breda | - | Helmond Sport | 1:0 (0:0) | |
| 29.11.2021 | 20:00 | FC Emmen | - | Almere City FC | 3:0 (2:0) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FC Volendam | 17 | 11 | 5 | 1 | 43:22 | 21 | 38 |
| 2 |
|
SBV Excelsior | 17 | 11 | 2 | 4 | 43:24 | 19 | 35 |
| 3 |
|
FC Emmen | 17 | 10 | 3 | 4 | 27:13 | 14 | 33 |
| 4 |
|
Jong Ajax | 17 | 10 | 2 | 5 | 42:30 | 12 | 32 |
| 5 |
|
De Graafschap | 17 | 9 | 3 | 5 | 28:20 | 8 | 30 |
| 6 |
|
ADO Den Haag | 17 | 11 | 2 | 4 | 37:20 | 17 | 29 |
| 7 |
|
FC Eindhoven | 17 | 9 | 2 | 6 | 32:24 | 8 | 29 |
| 8 |
|
FC Den Bosch | 17 | 8 | 1 | 8 | 20:26 | -6 | 25 |
| 9 |
|
Roda JC Kerkrade | 17 | 6 | 6 | 5 | 29:23 | 6 | 24 |
| 10 |
|
NAC Breda | 17 | 6 | 5 | 6 | 25:22 | 3 | 23 |
| 11 |
|
Jong PSV | 17 | 6 | 4 | 7 | 25:26 | -1 | 22 |
| 12 |
|
MVV Maastricht | 17 | 7 | 1 | 9 | 20:36 | -16 | 22 |
| 13 |
|
Jong AZ Alkmaar | 17 | 6 | 3 | 8 | 14:17 | -3 | 21 |
| 14 |
|
VVV-Venlo | 17 | 6 | 2 | 9 | 17:22 | -5 | 20 |
| 15 |
|
Jong FC Utrecht | 17 | 5 | 4 | 8 | 21:26 | -5 | 19 |
| 16 |
|
Telstar | 17 | 4 | 6 | 7 | 20:35 | -15 | 18 |
| 17 |
|
Almere City FC | 17 | 3 | 4 | 10 | 28:39 | -11 | 13 |
| 18 |
|
TOP Oss | 17 | 3 | 4 | 10 | 18:29 | -11 | 13 |
| 19 |
|
Helmond Sport | 17 | 4 | 3 | 10 | 15:28 | -13 | 12 |
| 20 |
|
FC Dordrecht | 17 | 2 | 4 | 11 | 19:41 | -22 | 10 |
| Promotie | |
| Play-offs | |
| Play-offs |
