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| 27.01.2023 | 20:00 | Telstar | - | Almere City FC | 0:1 (0:0) | |
| 20:00 | FC Den Bosch | - | MVV Maastricht | 3:3 (2:1) | ||
| 20:00 | FC Eindhoven | - | Heracles Almelo | 1:0 (1:0) | ||
| 20:00 | Helmond Sport | - | Jong Ajax | 1:1 (0:0) | ||
| 20:00 | NAC Breda | - | Jong AZ Alkmaar | 5:1 (1:0) | ||
| 20:00 | PEC Zwolle | - | TOP Oss | 4:1 (1:0) | ||
| 20:00 | Roda JC Kerkrade | - | FC Dordrecht | 1:0 (0:0) | ||
| 20:00 | VVV-Venlo | - | ADO Den Haag | 0:0 (0:0) | ||
| 30.01.2023 | 20:00 | Jong PSV | - | Willem II | 3:2 (0:1) | |
| 20:00 | Jong FC Utrecht | - | De Graafschap | 1:1 (1:0) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
PEC Zwolle | 22 | 17 | 2 | 3 | 55:23 | 32 | 53 |
| 2 |
|
Heracles Almelo | 22 | 15 | 2 | 5 | 58:27 | 31 | 47 |
| 3 |
|
FC Eindhoven | 22 | 11 | 6 | 5 | 36:28 | 8 | 39 |
| 4 |
|
Almere City FC | 22 | 12 | 3 | 7 | 34:27 | 7 | 39 |
| 5 |
|
VVV-Venlo | 22 | 10 | 6 | 6 | 31:30 | 1 | 36 |
| 6 |
|
MVV Maastricht | 22 | 10 | 5 | 7 | 40:38 | 2 | 35 |
| 7 |
|
Willem II | 22 | 9 | 6 | 7 | 33:25 | 8 | 33 |
| 8 |
|
Jong AZ Alkmaar | 22 | 9 | 5 | 8 | 35:31 | 4 | 32 |
| 9 |
|
NAC Breda | 22 | 9 | 4 | 9 | 34:36 | -2 | 31 |
| 10 |
|
Roda JC Kerkrade | 22 | 9 | 4 | 9 | 32:30 | 2 | 31 |
| 11 |
|
Telstar | 22 | 7 | 8 | 7 | 23:29 | -6 | 29 |
| 12 |
|
Jong PSV | 22 | 7 | 6 | 9 | 35:36 | -1 | 27 |
| 13 |
|
De Graafschap | 22 | 7 | 6 | 9 | 34:35 | -1 | 27 |
| 14 |
|
ADO Den Haag | 22 | 6 | 7 | 9 | 24:32 | -8 | 25 |
| 15 |
|
Jong Ajax | 22 | 5 | 9 | 8 | 36:39 | -3 | 24 |
| 16 |
|
FC Den Bosch | 22 | 7 | 2 | 13 | 32:44 | -12 | 23 |
| 17 |
|
FC Dordrecht | 22 | 6 | 5 | 11 | 24:37 | -13 | 23 |
| 18 |
|
Helmond Sport | 22 | 6 | 4 | 12 | 19:36 | -17 | 22 |
| 19 |
|
TOP Oss | 22 | 5 | 3 | 14 | 22:40 | -18 | 18 |
| 20 |
|
Jong FC Utrecht | 22 | 4 | 5 | 13 | 21:35 | -14 | 17 |
| Promotie | |
| Play-offs |
