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| 17.03.2023 | 20:00 | Jong AZ Alkmaar | - | FC Eindhoven | 1:1 (0:0) | |
| 20:00 | Helmond Sport | - | Telstar | 2:2 (0:1) | ||
| 20:00 | ADO Den Haag | - | Willem II | 1:3 (1:0) | ||
| 20:00 | FC Den Bosch | - | FC Dordrecht | 3:1 (2:0) | ||
| 20:00 | MVV Maastricht | - | Jong FC Utrecht | 1:0 (0:0) | ||
| 20:00 | TOP Oss | - | Heracles Almelo | 1:5 (0:0) | ||
| 20:00 | PEC Zwolle | - | NAC Breda | 2:0 (0:0) | ||
| 20:00 | Jong Ajax | - | Almere City FC | 0:2 (0:1) | ||
| 20:00 | Jong PSV | - | De Graafschap | 2:1 (0:1) | ||
| 19.03.2023 | 12:15 | VVV-Venlo | - | Roda JC Kerkrade | 1:1 (0:0) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
PEC Zwolle | 29 | 21 | 3 | 5 | 80:32 | 48 | 66 |
| 2 |
|
Heracles Almelo | 29 | 20 | 3 | 6 | 83:33 | 50 | 63 |
| 3 |
|
Almere City FC | 29 | 17 | 4 | 8 | 42:29 | 13 | 55 |
| 4 |
|
VVV-Venlo | 29 | 14 | 7 | 8 | 45:38 | 7 | 49 |
| 5 |
|
Willem II | 29 | 13 | 8 | 8 | 49:34 | 15 | 47 |
| 6 |
|
FC Eindhoven | 29 | 13 | 7 | 9 | 43:41 | 2 | 46 |
| 7 |
|
MVV Maastricht | 29 | 13 | 5 | 11 | 53:52 | 1 | 44 |
| 8 |
|
NAC Breda | 29 | 13 | 4 | 12 | 47:48 | -1 | 43 |
| 9 |
|
Jong AZ Alkmaar | 29 | 11 | 8 | 10 | 49:47 | 2 | 41 |
| 10 |
|
Telstar | 29 | 10 | 10 | 9 | 30:41 | -11 | 40 |
| 11 |
|
De Graafschap | 29 | 11 | 6 | 12 | 47:40 | 7 | 39 |
| 12 |
|
ADO Den Haag | 29 | 10 | 8 | 11 | 35:43 | -8 | 38 |
| 13 |
|
Roda JC Kerkrade | 29 | 11 | 5 | 13 | 39:40 | -1 | 38 |
| 14 |
|
Jong PSV | 29 | 9 | 8 | 12 | 45:49 | -4 | 35 |
| 15 |
|
Helmond Sport | 29 | 9 | 6 | 14 | 28:45 | -17 | 33 |
| 16 |
|
TOP Oss | 29 | 9 | 3 | 17 | 34:54 | -20 | 30 |
| 17 |
|
FC Den Bosch | 29 | 9 | 3 | 17 | 40:70 | -30 | 30 |
| 18 |
|
Jong Ajax | 29 | 6 | 10 | 13 | 45:56 | -11 | 28 |
| 19 |
|
FC Dordrecht | 29 | 7 | 5 | 17 | 32:51 | -19 | 26 |
| 20 |
|
Jong FC Utrecht | 29 | 5 | 5 | 19 | 27:50 | -23 | 20 |
| Promotie | |
| Play-offs |
