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| 18.04.2022 | 14:30 | Katwijk | - | AFC | 2:0 (1:0) | |
| 14:30 | Scheveningen | - | De Treffers | 3:0 (2:0) | ||
| 15:00 | ASWH | - | IJsselmeervogels | 0:2 (0:0) | ||
| 15:00 | Excelsior Maassluis | - | TEC | 1:1 (1:0) | ||
| 15:30 | Jong Sparta Rotterdam | - | Jong FC Volendam | 2:1 (0:0) | ||
| 17:00 | Spakenburg | - | Kozakken Boys | 3:1 (1:0) | ||
| 19.04.2022 | 20:00 | HHC Hardenberg | - | GVVV | 3:0 (0:0) | |
| 20:00 | Rijnsburgse Boys | - | Quick Boys | 3:0 (0:0) | ||
| 20:00 | Koninklijke HFC | - | Noordwijk | 2:1 (1:0) |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Katwijk | 26 | 17 | 5 | 4 | 54:25 | 29 | 56 |
| 2 |
|
Koninklijke HFC | 26 | 14 | 7 | 5 | 42:27 | 15 | 49 |
| 3 |
|
HHC Hardenberg | 26 | 14 | 4 | 8 | 41:32 | 9 | 46 |
| 4 |
|
Jong Sparta Rotterdam | 26 | 13 | 5 | 8 | 44:41 | 3 | 44 |
| 5 |
|
Rijnsburgse Boys | 26 | 13 | 3 | 10 | 52:33 | 19 | 42 |
| 6 |
|
AFC | 26 | 12 | 6 | 8 | 48:35 | 13 | 42 |
| 7 |
|
Quick Boys | 26 | 11 | 8 | 7 | 37:32 | 5 | 41 |
| 8 |
|
Noordwijk | 26 | 11 | 5 | 10 | 36:36 | 0 | 38 |
| 9 |
|
Scheveningen | 26 | 9 | 9 | 8 | 32:35 | -3 | 36 |
| 10 |
|
Spakenburg | 26 | 10 | 5 | 11 | 47:47 | 0 | 35 |
| 11 |
|
Excelsior Maassluis | 26 | 10 | 5 | 11 | 38:44 | -6 | 35 |
| 12 |
|
De Treffers | 26 | 10 | 3 | 13 | 29:34 | -5 | 33 |
| 13 |
|
IJsselmeervogels | 26 | 10 | 2 | 14 | 32:39 | -7 | 32 |
| 14 |
|
TEC | 26 | 8 | 7 | 11 | 34:48 | -14 | 31 |
| 15 |
|
Jong FC Volendam | 26 | 9 | 3 | 14 | 46:49 | -3 | 30 |
| 16 |
|
Kozakken Boys | 26 | 6 | 8 | 12 | 31:45 | -14 | 26 |
| 17 |
|
GVVV | 26 | 4 | 7 | 15 | 25:45 | -20 | 19 |
| 18 |
|
ASWH | 26 | 5 | 4 | 17 | 29:50 | -21 | 19 |
| Promotie en degradatie | |
| Promotie en degradatie | |
| Degradatie |
