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| 20.03.2021 | 17:00 | MFK Ružomberok | - | MFK Zemplín Michalovce | 2:0 (0:0) | |
| 17:00 | FC Nitra | - | FK Pohronie | 2:3 (1:1) | ||
| 17:00 | FK Senica | - | ŠKF Sereď | 1:0 (0:0) |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FK Pohronie | 24 | 5 | 11 | 8 | 33:34 | -1 | 26 |
| 2 |
|
MFK Ružomberok | 24 | 6 | 8 | 10 | 33:38 | -5 | 26 |
| 3 |
|
ŠKF Sereď | 24 | 6 | 7 | 11 | 23:40 | -17 | 25 |
| 4 |
|
FK Senica | 24 | 6 | 6 | 12 | 24:43 | -19 | 24 |
| 5 |
|
FC Nitra | 24 | 6 | 5 | 13 | 24:42 | -18 | 23 |
| 6 |
|
MFK Zemplín Michalovce | 24 | 5 | 8 | 11 | 23:45 | -22 | 23 |
| Promotie en degradatie | |
| Degradatie |
