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| 27.02.2021 | 14:00 | FC DAC 1904 | - | MFK Zemplín Michalovce | 2:1 (1:0) | |
| 14:00 | FK Pohronie | - | AS Trenčín | 0:1 (0:0) | ||
| 14:00 | MFK Ružomberok | - | FK Senica | 2:3 (1:2) | ||
| 14:00 | FC Nitra | - | Zlaté Moravce | 0:1 (0:1) | ||
| 17:00 | Spartak Trnava | - | MŠK Žilina | 2:1 (2:1) | ||
| 28.02.2021 | 15:00 | ŠKF Sereď | - | Slovan Bratislava | 0:5 (0:2) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Slovan Bratislava | 21 | 16 | 3 | 2 | 51:11 | 40 | 51 |
| 2 |
|
FC DAC 1904 | 21 | 13 | 5 | 3 | 47:25 | 22 | 44 |
| 3 |
|
Spartak Trnava | 21 | 11 | 2 | 8 | 32:27 | 5 | 35 |
| 4 |
|
MŠK Žilina | 21 | 10 | 4 | 7 | 46:31 | 15 | 34 |
| 5 |
|
Zlaté Moravce | 21 | 8 | 6 | 7 | 37:29 | 8 | 30 |
| 6 |
|
AS Trenčín | 21 | 6 | 7 | 8 | 28:38 | -10 | 25 |
| 7 |
|
MFK Ružomberok | 21 | 5 | 8 | 8 | 29:34 | -5 | 23 |
| 8 |
|
FC Nitra | 21 | 6 | 4 | 11 | 21:37 | -16 | 22 |
| 9 |
|
ŠKF Sereď | 21 | 5 | 7 | 9 | 22:38 | -16 | 22 |
| 10 |
|
FK Senica | 21 | 5 | 5 | 11 | 22:39 | -17 | 20 |
| 11 |
|
FK Pohronie | 21 | 3 | 10 | 8 | 26:31 | -5 | 19 |
| 12 |
|
MFK Zemplín Michalovce | 21 | 4 | 7 | 10 | 21:42 | -21 | 19 |
| Play-offs | |
| Promotie en degradatie |
