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| 26.03.2022 | 11:00 | 1922 Konyaspor | - | Kırklarelispor | 0:2 (0:1) | |
| 11:00 | Bucaspor 1928 | - | Pazarspor | 4:1 (2:1) | ||
| 12:00 | 24 Erzincanspor | - | Şanlıurfaspor | 2:1 (0:0) | ||
| 12:00 | Akhisar Belediyespor | - | Ankara Demirspor | 3:1 (1:1) | ||
| 12:00 | Isparta 32 SK | - | Eskişehirspor | 2:0 (0:0) | ||
| 12:00 | Pendikspor | - | Nazilli Belediyespor | 1:2 (0:1) | ||
| 12:00 | Tarsus Idman Yurdu | - | Karacabey Belediyespor | 2:0 (1:0) | ||
| 12:00 | Uşakspor | - | Kırşehir Belediyespor | 0:0 (0:0) | ||
| 12:00 | Zonguldak Kömürspor | - | Amed SK | 1:3 (0:1) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Pendikspor | 27 | 19 | 3 | 5 | 42:21 | 21 | 60 |
| 2 |
|
Isparta 32 SK | 28 | 14 | 5 | 9 | 34:25 | 9 | 47 |
| 3 |
|
Bucaspor 1928 | 29 | 13 | 6 | 10 | 45:37 | 8 | 45 |
| 4 |
|
Amed SK | 27 | 13 | 6 | 8 | 34:28 | 6 | 45 |
| 5 |
|
24 Erzincanspor | 28 | 12 | 6 | 10 | 46:36 | 10 | 42 |
| 6 |
|
Kırklarelispor | 27 | 10 | 11 | 6 | 34:22 | 12 | 41 |
| 7 |
|
Ankara Demirspor | 28 | 11 | 8 | 9 | 33:28 | 5 | 41 |
| 8 |
|
Tarsus Idman Yurdu | 28 | 11 | 7 | 10 | 33:28 | 5 | 40 |
| 9 |
|
Karacabey Belediyespor | 27 | 13 | 1 | 13 | 39:37 | 2 | 40 |
| 10 |
|
Nazilli Belediyespor | 28 | 10 | 10 | 8 | 28:27 | 1 | 40 |
| 11 |
|
Kırşehir Belediyespor | 28 | 8 | 12 | 8 | 29:25 | 4 | 36 |
| 12 |
|
Şanlıurfaspor | 27 | 8 | 10 | 9 | 35:32 | 3 | 34 |
| 13 |
|
Zonguldak Kömürspor | 29 | 8 | 10 | 11 | 32:38 | -6 | 34 |
| 14 |
|
Uşakspor | 27 | 8 | 10 | 9 | 26:35 | -9 | 34 |
| 15 |
|
Akhisar Belediyespor | 28 | 8 | 5 | 15 | 32:42 | -10 | 29 |
| 16 |
|
Pazarspor | 27 | 9 | 2 | 16 | 30:49 | -19 | 29 |
| 17 |
|
1922 Konyaspor | 29 | 6 | 10 | 13 | 33:43 | -10 | 28 |
| 18 |
|
Eskişehirspor | 28 | 5 | 6 | 17 | 25:57 | -32 | 18 |
| 19 |
|
Kastamonuspor | 0 | 0 | 0 | 0 | 0:0 | 0 | 0 |
| Promotie | |
| Play-offs | |
| Degradatie |
