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| 07.05.2022 | 18:30 | Comunicaciones de Buenos Aires | - | Ituzaingó | 2:1 (0:1) | |
| 20:30 | Acassuso | - | Dock Sud | 1:1 (0:0) | ||
| 08.05.2022 | 18:30 | Talleres (RdE) | - | Defensores Unidos de Zárate | 2:1 (2:0) | |
| 20:30 | Cañuelas | - | Fénix | 2:0 (1:0) | ||
| 20:30 | Justo José de Urquiza | - | Atlético San Miguel | 3:0 (1:0) | ||
| 20:30 | Colegiales de Munro | - | UAI Urquiza | 2:1 (1:1) | ||
| 20:30 | Deportivo Merlo | - | Villa San Carlos | 1:2 (0:1) | ||
| 09.05.2022 | 20:30 | Argentino de Quilmes | - | Armenio | 1:1 (1:0) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Comunicaciones de Buenos Aires | 12 | 7 | 3 | 2 | 21:9 | 12 | 24 |
| 2 |
|
Ituzaingó | 13 | 7 | 3 | 3 | 15:11 | 4 | 24 |
| 3 |
|
Armenio | 12 | 5 | 6 | 1 | 15:8 | 7 | 21 |
| 4 |
|
Fénix | 13 | 5 | 6 | 2 | 14:9 | 5 | 21 |
| 5 |
|
Talleres (RdE) | 13 | 6 | 3 | 4 | 18:16 | 2 | 21 |
| 6 |
|
Defensores Unidos de Zárate | 12 | 5 | 5 | 2 | 18:14 | 4 | 20 |
| 7 |
|
Colegiales de Munro | 12 | 5 | 3 | 4 | 18:16 | 2 | 18 |
| 8 |
|
Cañuelas | 12 | 5 | 2 | 5 | 12:12 | 0 | 17 |
| 9 |
|
Villa San Carlos | 12 | 4 | 4 | 4 | 14:13 | 1 | 16 |
| 10 |
|
Acassuso | 12 | 3 | 6 | 3 | 14:12 | 2 | 15 |
|
Justo José de Urquiza | 12 | 3 | 6 | 3 | 14:12 | 2 | 15 | |
| 12 |
|
Dock Sud | 12 | 4 | 3 | 5 | 14:16 | -2 | 15 |
| 13 |
|
Argentino de Quilmes | 12 | 2 | 6 | 4 | 12:15 | -3 | 12 |
| 14 |
|
Deportivo Merlo | 13 | 3 | 3 | 7 | 9:16 | -7 | 12 |
| 15 |
|
UAI Urquiza | 12 | 3 | 2 | 7 | 12:21 | -9 | 11 |
| 16 |
|
CA Los Andes | 12 | 1 | 6 | 5 | 8:16 | -8 | 9 |
| 17 |
|
Atlético San Miguel | 12 | 2 | 1 | 9 | 6:18 | -12 | 7 |
| Play-offs |
