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| 22.06.2022 | 21:00 | Atlético Paraná | - | Boca Unidos | 0:0 (0:0) | |
| 23.06.2022 | 00:30 | Sportivo Las Parejas | - | Juventud Antoniana | 1:0 (0:0) | |
| 01:00 | Unión de Sunchales | - | Gimnasia y Esgrima (CdU) | 1:2 (1:0) | ||
| 01:30 | Defensores Belgrano (VR) | - | Douglas Haig | 0:1 (0:0) | ||
| 02:30 | Gimnasia y Tiro de Salta | - | Juventud Unida de Gualeguaychú | 2:0 (1:0) | ||
| 19:00 | Defensores de Pronunciamiento | - | Racing de Córdoba | 0:0 (0:0) | ||
| 21:00 | San Martín de Formosa | - | Belgrano de San Francisco | 4:2 (0:2) | ||
| 24.06.2022 | 03:00 | Central Norte | - | Sarmiento de Resistencia | 2:0 (1:0) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Racing de Córdoba | 14 | 9 | 5 | 0 | 24:4 | 20 | 32 |
| 2 |
|
Central Norte | 14 | 8 | 5 | 1 | 18:6 | 12 | 29 |
| 3 |
|
Douglas Haig | 14 | 7 | 3 | 4 | 18:9 | 9 | 24 |
| 4 |
|
San Martín de Formosa | 14 | 7 | 3 | 4 | 22:14 | 8 | 24 |
| 5 |
|
Sarmiento de Resistencia | 14 | 6 | 6 | 2 | 14:6 | 8 | 24 |
| 6 |
|
Sportivo Las Parejas | 14 | 7 | 3 | 4 | 17:13 | 4 | 24 |
| 7 |
|
Gimnasia y Tiro de Salta | 14 | 7 | 2 | 5 | 13:11 | 2 | 23 |
| 8 |
|
Crucero del Norte | 14 | 6 | 4 | 4 | 15:19 | -4 | 22 |
| 9 |
|
Gimnasia y Esgrima (CdU) | 14 | 5 | 4 | 5 | 15:16 | -1 | 19 |
| 10 |
|
Unión de Sunchales | 14 | 4 | 3 | 7 | 14:19 | -5 | 15 |
| 11 |
|
Belgrano de San Francisco | 14 | 4 | 3 | 7 | 12:17 | -5 | 15 |
| 12 |
|
Boca Unidos | 14 | 3 | 6 | 5 | 10:16 | -6 | 15 |
| 13 |
|
Defensores de Pronunciamiento | 14 | 3 | 5 | 6 | 9:16 | -7 | 14 |
| 14 |
|
Juventud Antoniana | 15 | 3 | 4 | 8 | 7:18 | -11 | 13 |
| 15 |
|
Atlético Paraná | 14 | 2 | 6 | 6 | 10:14 | -4 | 12 |
| 16 |
|
Defensores Belgrano (VR) | 15 | 3 | 3 | 9 | 14:20 | -6 | 12 |
| 17 |
|
Juventud Unida de Gualeguaychú | 14 | 3 | 1 | 10 | 10:24 | -14 | 10 |
| Play-offs |
