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| 23.11.1941 | Arenas de Getxo | - | Real Valladolid | 1:4 | ||
| Racing Santander | - | Real Unión | 3:0 | |||
| Sporting Gijón | - | Barakaldo CF | 2:0 | |||
| UD Salamanca | - | Racing Ferrol | 3:1 | |||
| AD Ferroviaria | - | Real Zaragoza | 1:1 | |||
| CD Constància | - | CA Osasuna | 2:2 | |||
| CE Sabadell | - | Deportivo Alavés | 1:1 | |||
| Levante UD | - | Girona FC | 1:2 | |||
| CD Málacitano | - | Real Murcia | 1:0 | |||
| UD Cartagena | - | AD Ceuta | 0:0 | |||
| Cádiz CF | - | Real Betis | 3:3 | |||
| Elche CF | - | Xerez FC | 3:0 |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Real Murcia | 9 | 6 | 1 | 2 | 28:15 | 13 | 13:5 |
| 2 |
|
Real Betis | 9 | 5 | 3 | 1 | 26:15 | 11 | 13:5 |
| 3 |
|
CE Sabadell | 9 | 5 | 3 | 1 | 19:8 | 11 | 13:5 |
| 4 |
|
Sporting Gijón | 9 | 5 | 3 | 1 | 25:17 | 8 | 13:5 |
| 5 |
|
Girona FC | 9 | 5 | 2 | 2 | 20:13 | 7 | 12:6 |
| 6 |
|
UD Salamanca | 9 | 6 | 0 | 3 | 19:16 | 3 | 12:6 |
| 7 |
|
CD Málacitano | 9 | 4 | 3 | 2 | 15:9 | 6 | 11:7 |
| 8 |
|
Deportivo Alavés | 9 | 5 | 1 | 3 | 17:14 | 3 | 11:7 |
| 9 |
|
CD Constància | 9 | 4 | 2 | 3 | 17:11 | 6 | 10:8 |
| 10 |
|
Racing Santander | 9 | 3 | 4 | 2 | 18:13 | 5 | 10:8 |
| 11 |
|
Barakaldo CF | 9 | 4 | 2 | 3 | 17:18 | -1 | 10:8 |
| 12 |
|
Real Valladolid | 9 | 4 | 1 | 4 | 22:15 | 7 | 9:9 |
| 13 |
|
Racing Ferrol | 9 | 4 | 1 | 4 | 21:15 | 6 | 9:9 |
| 14 |
|
AD Ceuta | 9 | 3 | 3 | 3 | 19:15 | 4 | 9:9 |
| 15 |
|
Real Zaragoza | 9 | 3 | 3 | 3 | 16:16 | 0 | 9:9 |
| 16 |
|
Elche CF | 9 | 3 | 3 | 3 | 16:24 | -8 | 9:9 |
| 17 |
|
Cádiz CF | 9 | 3 | 2 | 4 | 17:15 | 2 | 8:10 |
| 18 |
|
Arenas de Getxo | 9 | 4 | 0 | 5 | 16:23 | -7 | 8:10 |
| 19 |
|
CA Osasuna | 9 | 2 | 3 | 4 | 18:18 | 0 | 7:11 |
| 20 |
|
Xerez FC | 9 | 2 | 2 | 5 | 19:28 | -9 | 6:12 |
| 21 |
|
AD Ferroviaria | 9 | 2 | 1 | 6 | 12:18 | -6 | 5:13 |
| 22 |
|
Levante UD | 9 | 2 | 1 | 6 | 12:33 | -21 | 5:13 |
| 23 |
|
UD Cartagena | 9 | 0 | 3 | 6 | 10:29 | -19 | 3:15 |
| 24 |
|
Real Unión | 9 | 0 | 1 | 8 | 13:34 | -21 | 1:17 |
